Indications:
Ticamet Inhaler is recommended for the routine treatment of asthma when a combination product (long-acting β2-agonist and inhaled corticosteroid) is deemed suitable. It’s beneficial for patients not adequately controlled with inhaled corticosteroids alone and those requiring both inhaled corticosteroid and long-acting β2-agonist for effective asthma management.
Pharmacology:
Ticamet combines Salmeterol Xinafoate, a selective long-acting beta-2 agonist, and Fluticasone Propionate, a corticosteroid primarily active in the lungs. While Salmeterol provides protection against symptoms, Fluticasone improves lung function and prevents asthma exacerbations. This formulation offers convenience to patients on combined therapy.
Dosage:
- Inhaler:
- For adults and adolescents (12 years and older): 2 puffs twice daily with varying strengths depending on the severity.
- For children (4-12 years): 2 puffs twice daily with a specified strength.
- Inhalation capsule (for asthma):
- For adults and adolescents (12 years and older): Twice daily with strength determined by asthma severity.
- For pediatric patients (4 to 11 years): Twice daily with specified strength.
Administration:
Correct Inhaler usage is crucial for optimal asthma management. Following the proper steps ensures effective delivery of medication to the lungs, reducing the risk of asthma attacks.
Interaction:
Caution is advised with β-blockers in asthma patients. While clinically significant interactions are unlikely with inhaled dosing, co-administration with strong CYP3A4 inhibitors may increase systemic exposure to Fluticasone Propionate.
Contraindications:
Ticamet Inhaler is contraindicated in patients with hypersensitivity to its components and should not be used as the primary treatment for acute asthma episodes.
Side Effects:
Expected side effects include those associated with Salmeterol and Fluticasone Propionate, which are generally manageable. Serious adverse events are rare but should be monitored.
Pregnancy & Lactation:
Use during pregnancy and lactation should be carefully considered, weighing benefits against potential risks to the fetus or child.
Precautions & Warnings:
Patients with unstable or acute asthma should not initiate treatment with Ticamet Inhaler. Careful monitoring is advised for asthma-related adverse events, and immediate medical attention is necessary for paradoxical bronchospasm.
Use in Special Populations:
Special consideration is needed for pediatric patients due to potential effects on growth velocity. Regular review of the patient’s condition is essential to adjust the dosage as needed.
Overdose Effects:
While human overdose data is limited, symptoms may include those associated with Salmeterol and Fluticasone Propionate. Prompt medical attention is necessary in case of overdose.
Therapeutic Class:
Ticamet belongs to the therapeutic class of long-acting selective β-adrenoceptor stimulants and respiratory corticosteroids.
Storage Conditions:
Store Ticamet Inhaler below 30°C, away from direct sunlight, and out of reach of children. Avoid puncturing or incinerating the canister, even when empty.
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