Indications
Flexi SR serves as a solution for alleviating pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, toothaches, trauma, and lumbago.
Pharmacology
Aceclofenac, a non-steroidal drug with potent anti-inflammatory and analgesic properties, acts by inhibiting the cyclooxygenase enzyme responsible for prostaglandin production. Following oral intake, it undergoes rapid and complete absorption without alteration.
Dosage & Administration
- Extended Release Tablet: For adults, the recommended daily dose is one 200 mg Aceclofenac tablet as directed by the physician.
- Film Coated Tablet: Adults should take 100 mg twice daily.
Adhere to medical advice for optimal medication consumption.
Interactions
While significant drug interactions are rare, vigilance is necessary when combining with:
- Lithium and Digoxin: Potential elevation in plasma concentration.
- Diuretics: May impact diuretic activity.
- Anticoagulants: Possible enhancement of anticoagulant effects.
- Methotrexate: Potential increase in plasma methotrexate levels.
Contraindications
Avoid Aceclofenac in individuals with known hypersensitivity or those prone to asthma attacks triggered by aspirin or NSAIDs.
Side Effects
Flexi SR, being a non-steroidal drug with anti-inflammatory and analgesic qualities, inhibits the cyclooxygenase enzyme crucial for prostaglandin synthesis. Following oral ingestion, it’s promptly absorbed without alteration.
Pregnancy & Lactation
Exercise caution with Aceclofenac during pregnancy and lactation, prioritizing its use only if benefits outweigh potential fetal risks.
Precautions & Warnings
Exercise caution in patients with active or suspected peptic ulcers, gastrointestinal bleeding, moderate to severe hepatic impairment, or cardiac/renal issues. Additional care is necessary for patients experiencing dizziness or urticaria.
Use in Special Populations
Clinical data regarding Flexi SR usage in children are lacking.
Therapeutic Class
Flexi SR falls under Drugs for Osteoarthritis, Drugs for Rheumatoid Arthritis, and Non-steroidal Anti-inflammatory Drugs (NSAIDs).
Storage Conditions
Store in a dry place, shielded from light and heat, and out of children’s reach.
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