Indications
Flexi is recommended for alleviating pain and reducing inflammation associated with various conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, toothache, trauma, and lumbago.
Pharmacological Profile
Aceclofenac, a non-steroidal medication, possesses anti-inflammatory and analgesic properties. It acts as a potent inhibitor of cyclooxygenase enzyme, crucial in prostaglandin production. Upon oral intake, it undergoes rapid and complete absorption without alteration.
Dosage & Administration
- Extended-release tablet: Adults are advised to take one 200 mg Aceclofenac tablet daily, or as directed by a healthcare professional.
- Film-coated tablet: The recommended dosage for adults is 100 mg, twice daily.
Follow physician’s advice for medication usage.
Interactions
Although no significant drug interactions have been noted, cautious monitoring is advised, especially when Aceclofenac is used concomitantly with:
- Lithium and Digoxin: Potential increase in plasma concentration.
- Diuretics: Possible interaction with diuretic activity.
- Anticoagulants: Enhanced anticoagulant effect.
- Methotrexate: Potential elevation in methotrexate plasma levels.
Contraindications
Aceclofenac should be avoided in patients with known hypersensitivity to the drug or in those who experience asthma attacks triggered by aspirin or NSAIDs.
Side Effects
Flexi, being a non-steroidal medication with anti-inflammatory and analgesic attributes, may entail certain side effects.
Pregnancy & Lactation
Unless the benefits outweigh the risks, it’s advisable to refrain from using Aceclofenac during pregnancy and lactation.
Precautions & Warnings
Exercise caution in patients with active or suspected peptic ulcer, gastrointestinal bleeding, moderate to severe hepatic impairment, and cardiac or renal issues. Patients experiencing dizziness or urticaria should also use the medication cautiously.
Use in Special Populations
Clinical data on the use of Flexi in children are not available.
Therapeutic Class
Flexi belongs to the category of drugs used for osteoarthritis, rheumatoid arthritis, and falls under the classification of non-steroidal anti-inflammatory drugs (NSAIDs).
Storage Conditions
Store in a dry place, shielded from light and heat, and ensure it’s out of reach of children.
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