Amlex

Indications

Amlex is primarily used to treat aphthous ulcers (canker sores) by promoting faster healing and reducing discomfort.

Pharmacology

The exact mechanism by which Amlexanox accelerates the healing of aphthous ulcers remains unclear. However, research indicates that it inhibits the release of inflammatory mediators, such as histamine and leukotrienes, from immune cells, which helps in reducing inflammation. Amlexanox also demonstrates anti-allergic and anti-inflammatory properties in animal studies. After oral administration, it reaches peak serum levels in about 2.4 hours, with a half-life of 3.5 hours.

Dosage & Administration

• Apply Amlex oral paste promptly after symptoms of an aphthous ulcer appear.
• Use it four times a day, preferably after meals and before bedtime.
• Dry the ulcer area gently with a clean cloth, apply the paste with a moistened fingertip, and repeat if necessary.
• Continue use until the ulcer heals. If there is no significant healing or pain relief after 10 days, consult your physician.

Always follow the advice of a registered healthcare provider.

Contraindications

Amlex is contraindicated in patients who are hypersensitive to Amlexanox or any other ingredients in the formulation.

Side Effects

Some patients may experience mild discomfort, including transient pain, stinging, or burning at the application site. Rare side effects (<1%) include contact mucositis, nausea, and diarrhea.

Pregnancy & Lactation

Amlex is classified as US FDA Pregnancy Category B, with no adverse effects observed in animal studies. However, it should be used during pregnancy only if absolutely necessary. Caution is advised during breastfeeding as Amlexanox has been detected in the milk of lactating rats.

Precautions & Warnings

Wash hands thoroughly after applying the paste. If any rash or mucositis develops, discontinue use immediately.

Use in Special Populations

• Pediatric Use: Safety and effectiveness have not been established for pediatric patients.

Overdose Effects

Ingesting a full tube of Amlex paste is unlikely to cause toxic effects but may lead to gastrointestinal issues like nausea and diarrhea.

Storage Conditions

Store Amlex in a cool, dry place away from light and out of the reach of children.