Urilax 100

Indications

Urilax is indicated for the relief of symptoms associated with dysuria, urgency, nocturia, suprapubic pain, urinary frequency, and incontinence. It is effective in conditions such as cystitis, prostatitis, urethritis, and urethrocystitis.

• Use only under the guidance of a registered physician.

Description

Urilax is a spasmolytic flavone derivative that relaxes smooth muscle in the urinary tract. As a competitive muscarinic receptor antagonist, it is specifically indicated for treating overactive bladder symptoms, including urge urinary incontinence, urgency, and frequent urination. Muscarinic receptors play a crucial role in mediating functions such as bladder contractions and salivary secretion.

Pharmacology

Flavoxate acts as a direct antagonist at muscarinic acetylcholine receptors in organs that are cholinergically innervated. Its anticholinergic-parasympatholytic properties reduce smooth muscle tone in the bladder, leading to fewer voids, decreased episodes of urge incontinence, and improved urine retention, facilitating a higher volume per void.

Dosage & Administration

Adults and children over 12 years:
100 mg to 200 mg three times daily. The dosage may be reduced as symptoms improve.

Pediatric Use:
Safety and effectiveness for children under 12 years have not been established.

• Use only under the guidance of a registered physician.

Contraindications

Flavoxate is contraindicated in patients with obstructive conditions such as pyloric or duodenal obstruction, intestinal lesions, ileus, achalasia, gastrointestinal hemorrhage, and lower urinary tract obstructive uropathies.

Side Effects

Gastrointestinal: Nausea, vomiting, dry mouth.
CNS: Vertigo, headache, confusion (especially in the elderly), drowsiness, nervousness.
Hematologic: Reversible leukopenia upon discontinuation.
Cardiovascular: Tachycardia, palpitations.
Allergic: Urticaria, dermatoses, eosinophilia, hyperpyrexia.
Ophthalmic: Increased intraocular pressure, blurred vision, accommodation disturbances.

Pregnancy & Lactation

Pregnancy Category B. Use during pregnancy only if clearly needed. It is unclear whether this drug is excreted in breast milk, so caution is advised when administering to nursing mothers.

Precautions & Warnings

Caution is recommended for patients with suspected glaucoma.

Therapeutic Class

BPH / Urinary retention / Urinary incontinence

Storage Conditions

Store below 30°C, away from light and moisture. Keep out of reach of children.