Tofen Eye Drop

Indications

Tofen Eye Drops are designed to alleviate the symptoms of allergic conjunctivitis, such as itchy, watery, red, and swollen eyes and eyelids. They are effective in treating various conditions, including vernal keratoconjunctivitis, blepharitis, blepharo-conjunctivitis, and giant papillary conjunctivitis.

Pharmacology

Tofen Eye Drops contain ketotifen, a powerful anti-allergic agent known for its non-competitive histamine (H1) receptor antagonism. Ketotifen blocks the release of key inflammatory mediators like histamine, leukotrienes, and prostaglandins. Additionally, it stabilizes mast cells and reduces the activation and degranulation of eosinophils.

Dosage & Administration

• Adults and children aged 3 years and older: Apply 1 drop in the affected eye(s) twice daily, ideally every 8-12 hours. Do not exceed twice per day.
• Children under 3 years: Consult a physician for appropriate dosage.

Always follow your healthcare provider’s instructions.

Interactions

Allow a minimum of 5 minutes between applying Tofen Eye Drops and any other eye medications.

Contraindications

Tofen Eye Drops should not be used if you have a known hypersensitivity to ketotifen or any of the other ingredients.

Side Effects

Possible side effects include burning, stinging, blurred vision, dry eyes, eyelid issues, conjunctivitis, eye pain, sensitivity to light, and subconjunctival hemorrhage.

Pregnancy & Lactation

While data on ketotifen use during pregnancy is limited, it is advised to use caution. Systemic levels are low after ocular administration. Although ketotifen can be found in breast milk in small amounts, it is considered safe for use during lactation.

Precautions & Warnings

Tofen Eye Drops contain benzalkonium chloride, which can be absorbed by soft contact lenses. Remove contact lenses before applying the drops and wait at least 15 minutes before reinserting them.

Overdose Effects

There have been no reported cases of overdose. Ingesting the contents of a 5 ml bottle is equivalent to 60% of the recommended oral dose for a 3-year-old child. Clinical studies indicate no serious effects from oral ingestion of up to 20 mg of Tofen.

Therapeutic Class

Ophthalmic Non-Steroidal Drugs

Storage Conditions

Store in a cool, dry place away from light and moisture. Keep out of reach of children. Avoid touching the dropper tip to any surface to prevent contamination. Discard 30 days after first opening.