Tofen

Indications

• Tofen is prescribed for managing allergic conditions including:
  • Bronchial asthma: Used as a preventive measure.
  • Allergic rhinitis and conjunctivitis: For symptomatic relief.
  • Neurofibroma-related symptoms: Alleviates itching, pain, and tenderness.
  • Hay fever and urticaria: Provides relief from allergic reactions.

Pharmacology

• Ketotifen, the active ingredient, offers:
  • Anti-anaphylactic effects: Helps prevent asthma attacks.
  • Histamine inhibition: Provides long-term relief from allergic reactions.
  • Mast cell stabilization: Effective in reducing asthma frequency and severity.

Dosage & Administration

• Adults: 1 mg twice daily with food, adjustable to 2 mg twice daily for severe cases.
• Children (3 years and older): 1 mg twice daily with food. Start with 0.5 to 1 mg at night if sedation occurs.
• Elderly: Same dosage as adults or as prescribed by a physician.

Interactions

• Tofen may enhance the effects of sedatives, hypnotics, antihistamines, and alcohol. Avoid combining with oral antidiabetic agents due to potential platelet count reduction.

Contraindications

• Avoid use in cases of hypersensitivity to Ketotifen or when combined with oral antidiabetic agents. Safety during pregnancy and lactation is not well-established.

Side Effects

• Common side effects include drowsiness, dry mouth, and dizziness, which typically resolve after a few days.

Pregnancy & Lactation

• Pregnancy: Use is not recommended due to insufficient safety data.
• Lactation: Safety during breastfeeding is unclear; consult a healthcare provider.

Precautions & Warnings

• Continue previous treatments for at least two weeks after starting Tofen to prevent asthma exacerbation. Avoid operating vehicles or machinery until the drug’s effects are known. Avoid alcohol.

Overdose Effects

• Symptoms may include confusion, drowsiness, headache, bradycardia, and respiratory depression. Gastric lavage and supportive care are recommended.

Therapeutic Class

• Cromoglycate and related drugs.

Storage Conditions

• Store in a cool, dry place away from light. Keep out of reach of children.

Chemical Structure

• Molecular Formula: C19H19NOS
• Structure: Ketotifen Fumarate (Oral).

Common Questions about Tofen 1 mg/5 ml Syrup

• What is Tofen 1 mg/5 ml Syrup? An antihistamine and mast cell stabilizer for allergic conditions like conjunctivitis and asthma.
• Uses? Treats bronchial asthma, rhinitis, conjunctivitis, hay fever, and urticaria.
• Pregnancy? Use during pregnancy is not advised.
• Breastfeeding? Safety unknown; consult your doctor.
• Kidney & Liver Function? No data available; consult a doctor before use.