Timotor 10
60.00৳ Strip
- Explore Trimebutine Maleate, a proven treatment for irritable bowel syndrome and postoperative paralytic ileus.
- Noncompetitive spasmolytic agent with potent anti-serotonin activity, particularly on ‘mu’ receptors.
- Regulates abnormal intestinal activity while preserving normal motility.
- Recommended dosage: 100 mg to 200 mg, three times daily before meals.
- Well-tolerated with minimal reported side effects like dry mouth and occasional gastrointestinal discomfort.
- Caution advised during pregnancy and lactation; avoid if hypersensitive to trimebutine maleate.
- Store in a cool, dry place away from light and moisture; keep out of reach of children.
Brand
|
Square Pharmaceuticals PLC |
|---|---|
Generics
|
Trimebutine Maleate |
Type
|
Tablet |
Indications
Trimebutine maleate is indicated for treating and relieving symptoms associated with irritable bowel syndrome (spastic colon) and postoperative paralytic ileus. It helps accelerate the resumption of intestinal transit following abdominal surgery.
Pharmacology
Trimebutine maleate acts as a noncompetitive spasmolytic agent with moderate affinity for opiate receptors and significant anti-serotonin activity, particularly on ‘mu’ receptors. It regulates abnormal intestinal activity by enhancing synchronization between electrophysiological spikes and contractions in isolated guinea pig strips of colon and ileum, without altering normal motility.
Dosage & Administration
For adults, the recommended dosage is 100 mg to 200 mg, three times daily before meals, as advised by a healthcare professional.
Interactions
Trimebutine maleate may prolong d-tubocurarine-induced curarization. No other drug interactions have been observed during clinical trials.
Contraindications
This medication is contraindicated in patients with known hypersensitivity to trimebutine maleate or any excipient.
Side Effects
Trimebutine maleate is generally well tolerated. Infrequently reported adverse effects may include dry mouth, unpleasant taste, diarrhea, dyspepsia, epigastric pain, nausea, constipation, drowsiness, fatigue, dizziness, and sensations of temperature change.
Pregnancy & Lactation
Although teratological studies have not shown adverse effects on pregnancy outcomes, the use of trimebutine maleate in pregnant women is not recommended. Its excretion into breast milk is unknown; therefore, caution is advised during breastfeeding.
Precautions & Warnings
Special precautions should be taken in elderly patients and those who are pregnant or breastfeeding.
Overdose Effects
No cases of overdose have been reported; however, if oral overdosage occurs, gastric lavage is recommended. Treatment should address observed symptoms.
Therapeutic Class
Trimebutine maleate belongs to the class of anticholinergics.
Storage Conditions
Store in a cool, dry place away from light and moisture. Keep out of reach of children.
Reviews
There are no reviews yet.