Rynex Spray

Indications

Rynex is prescribed for relief from nasal congestion associated with conditions such as acute or chronic rhinitis, the common cold, sinusitis, upper respiratory allergies, nosebleeds, and hay fever. Additionally, it serves as a nasal decongestant in cases of otitis media.

• “Consume medication according to a registered physician’s advice.”

Pharmacology

Oxymetazoline Hydrochloride, a sympathomimetic amine derivative, acts as an imidazoline with direct agonist activity on α-adrenoceptors, though it doesn’t interact with β-adrenoceptors. When applied topically to the nasal mucosa, it induces rapid and prolonged vasoconstriction in arterioles, decreasing blood flow and reducing mucosal swelling. This action improves airway patency and enhances nasal sinus drainage.

Dosage

Oxymetazoline Nasal Spray

• Adults and children aged 6 and above: Administer 2-3 sprays per nostril twice daily for a maximum of 3-5 days.
• Elderly: No dosage adjustments are necessary for nasal administration.
• Children under 6 years: This product is unsuitable for children below this age.

Oxymetazoline Nasal Drops

• Adults and children aged 6 and older: Apply 2-3 drops of 0.05% solution in each nostril twice daily, morning and evening.
• Children aged 2-5 years: Administer 2-3 drops of 0.025% solution in each nostril twice daily, morning and evening.
• “Consume medication according to a registered physician’s advice.”

Administration

Nasal Spray Usage

1. Gently shake the bottle and remove the dust cover.
2. Hold the spray with the forefinger and middle finger on either side of the nozzle and the thumb underneath. Press down until a fine spray appears. If unused for a week or more, press the nozzle several times until a mist appears.
3. Blow the nose gently to clear the nostrils.
4. Close one nostril, insert the applicator into the other nostril, slightly tilting the head forward. Breathe in and press down on the applicator to release a spray.
5. Exhale through the mouth.
6. Repeat for each nostril as needed.

Cleaning Instructions

To maintain the nasal spray, clean it at least once per week:

1. Remove the dust cover.
2. Carefully pull off the applicator.
3. Wash the dust cover and applicator with warm water, shake off excess water, and allow them to air dry.
4. Reattach the applicator and dust cover once dry.

• “Consume medication according to a registered physician’s advice.”

Drug Interactions

Rynex Nasal preparation should not be used in patients undergoing treatment with MAO inhibitors or within 14 days of stopping such treatment.

Contraindications

This medication is not recommended for patients with cardiovascular disease, hyperthyroidism, prostatic enlargement, angle-closure glaucoma, or any known hypersensitivity to its ingredients.

Side Effects

Some users may experience temporary irritation, dry mouth, or throat discomfort. Additional side effects may include mild burning, stinging, sneezing, or increased nasal discharge.

Pregnancy & Lactation

Although safety during pregnancy and lactation has not been firmly established, Oxymetazoline Hydrochloride Nasal Spray is generally not believed to pose a risk during these periods.

Precautions & Warnings

Avoid contact with the eyes. Do not use the spray beyond seven days without consulting a healthcare professional. Prolonged or frequent use may lead to recurring or worsening nasal congestion.

Overdose Effects

An overdose can lead to local irritation and rebound congestion. Treatment is typically symptomatic only.

Therapeutic Class

This product falls under Nasal Antihistamines, Nasal Decongestants, and Other Nasal Preparations.

Storage Conditions

Store below 30°C in a dry area, away from light. Do not refrigerate or freeze. Keep out of reach of children.