Indications:
- Addressing infertility in both men and women, including conditions like poor ovarian reserve and polycystic ovary syndrome.
- Managing various neurological disorders such as myopathy, ataxia, Parkinson’s disease, and Alzheimer’s disease.
- Supporting cardiovascular health by aiding in conditions like congestive heart failure, hypertension, and angina.
- Other applications include managing periodontal gum disease, diabetes, and enhancing exercise performance.
Pharmacology:
- Coenzyme Q10 (Ubidecarenone) is a vital substance for cellular respiration and ATP production, found in every cell of the body.
- It is most needed in metabolically active tissues like the heart, immune system, and muscles.
- Absorption is optimized when taken with high-lipid content food, aiding its distribution to various tissues.
- Metabolism occurs in all tissues, with a significant portion excreted in feces and bile.
Dosage & Administration:
- Recommended dosages vary depending on the condition being treated, ranging from 100 mg to 2400 mg per day.
- It is advisable to divide the total daily dose into multiple smaller doses to reduce side effects.
Interaction:
- Potential interactions include those with statins, warfarin, beta-blockers, antidiabetic medications, and doxorubicin.
Contraindications:
- Avoid use in patients allergic to Coenzyme Q10 or its components and those scheduled for surgery within two weeks.
Side Effects:
- Mild side effects may include stomach upset, loss of appetite, nausea, vomiting, diarrhea, and allergic skin reactions.
Pregnancy & Lactation:
- Not recommended during pregnancy and breastfeeding.
Precautions & Warnings:
- Monitor blood sugar and blood pressure levels in diabetic or hypoglycemic patients and those with low blood pressure.
Therapeutic Class:
- Considered under the category of Herbal and Nutraceuticals, Supplements & adjuvant therapy.
Storage Conditions:
- Store in a dry place away from light and heat, and keep out of reach of children.
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