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Repres SR

50.30৳ Strip

  • Experience relief from essential hypertension and fluid retention with Repres SR.
  • Effective diuretic and antihypertensive properties reduce vascular resistance for improved heart health.
  • Optimal daily dosage ensures maximum efficacy in managing hypertension and related conditions.
  • Prioritize safety with comprehensive cautionary advice and contraindications.
Brand

Square Pharmaceuticals PLC

Generics

Indapamide

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Description

Indications

Repres SR serves as a valuable treatment for essential hypertension. It effectively manages hypertension even in patients with compromised renal function, albeit with reduced diuretic impact. Additionally, Repres SR is beneficial for addressing salt and fluid retention linked with congestive heart failure.

Pharmacology

Indapamide, a diuretic antihypertensive, demonstrates vasodilatory effects, likely by impeding the passage of calcium and other ions (sodium, potassium) across cell membranes. Its extra-renal antihypertensive action diminishes vascular hyperreactivity, lowering total peripheral and arteriolar resistance.

Dosage & Administration

Recommended dosage entails one tablet daily, preferably taken in the morning. In more severe cases, combining Indapamide with other antihypertensive agents may be considered. However, its safety and efficacy in pediatric patients remain unestablished.

Interactions

Repres SR may enhance or complement the action of other antihypertensive medications. Additionally, it might decrease arterial responsiveness to norepinephrine. Concomitant use of diuretics like Repres SR with lithium is discouraged due to potential renal clearance reduction and heightened risk of lithium toxicity.

Contraindications

Avoid Repres SR in cases of hypersensitivity to sulfonamides, severe renal failure, hepatic encephalopathy or severe hepatic failure, and hypokalemia.

Side Effects

Possible side effects of Repres SR encompass headache, anorexia, gastric irritation, nausea, vomiting, constipation, and diarrhea.

Pregnancy & Lactation

Due to insufficient data from well-controlled studies, Indapamide is not recommended for pregnant women. Breastfeeding mothers should refrain from taking Indapamide.

Precautions & Warnings

Routine monitoring of potassium and uric acid serum levels is advisable, particularly in individuals predisposed to or sensitive to hypokalemia and those with gout history. Although allergic manifestations were not reported during clinical trials, patients with sulfonamide derivative allergies require close monitoring.

Overdose Effects

Symptoms of overdose may include allergies, skin rashes, epigastric pain, nausea, photosensitivity, dizziness, weakness, and paraesthesia. Treatment involves supportive and symptomatic measures, focusing on correcting electrolyte imbalances.

Therapeutic Class

Repres SR falls under the category of thiazide diuretics and related drugs.

Storage Conditions

Store Repres SR in a cool, dry place, shielded from light and moisture.

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