Norvis

Indications

Norvis serves as an antispasmodic medication targeting muscle spasms in various bodily systems, including the intestine, biliary system, bladder, and uterus. It’s instrumental in alleviating pain associated with functional disorders of the digestive tract and biliary system. Additionally, Norvis finds application in managing spasm and pain related to urological and gynecological conditions.

Pharmacology

Norvis contains Tiemonium Methylsulphate, a competitive antagonist of Acetylcholine and Histamine, which strengthens calcium bonds with membrane phospholipids and proteins. By inhibiting intracellular contractile proteins in visceral cells, it effectively suppresses visceral spasm and associated pain.

Dosage & Administration

For tablets/syrup:

• Adults typically take 2-6 tablets or 3-9 teaspoonfuls of syrup daily in divided doses.
• Children’s dosage ranges from 3 ml/kg to 6 mg/kg of body weight daily in divided doses.

For injection:

• Administer 1 Tiemonium Methylsulphate Injection three times daily via intravenous or intramuscular route.

For suppository:

• Use 20 mg Tiemonium Methylsulphate suppository two or three times daily via rectal route.

Interaction

Consult a registered physician before combining Norvis tablets with other medications to mitigate potential drug interactions.

Contraindications

Avoid Norvis in conditions involving urethroprostatic disorder with a risk of urine retention. It’s contraindicated in patients at risk of angle closure glaucoma.

Side Effects

Norvis may induce hypotension and tachycardia in certain individuals.

Pregnancy & Lactation

While animal studies didn’t reveal teratogenic effects of Tiemonium Methylsulphate, caution is advised during nursing. No deformities have been reported with normal use.

Precautions & Warnings

Exercise caution when treating patients with prostate disorders, chronic bronchitis, coronary insufficiency, ambient hyperthermia, renal, and hepatic insufficiency. Visual disturbances associated with Norvis may impair driving or machine operation.

Use in Special Populations

The safety and effectiveness of Norvis in pediatric patients haven’t been established. However, its efficacy and safety remain consistent with increasing age.

Overdose Effects

Data regarding Norvis tablet overdose is unavailable.

Therapeutic Class

Norvis belongs to the class of Anticholinergics, offering targeted relief from muscle spasms.

Storage Conditions

Store Norvis in a dry place, shielded from light and heat, and ensure it’s out of reach of children.