Nitazox
30.00৳ Strip
- Effective treatment for diarrhea caused by Cryptosporidium parvum, Giardia lamblia, and Entamoeba histolytica
- Synthetic antiprotozoal that disrupts essential metabolic processes
- Recommended for both children and adults
- Should be taken with food for enhanced absorption
- Consult a healthcare professional for proper dosage and safety
Brand
|
Incepta Pharmaceuticals Ltd |
|---|---|
Generics
|
Nitazoxanide |
Type
|
Tablet |
Indications
Nitazox is prescribed for treating diarrhea caused by Cryptosporidium parvum, Giardia lamblia, and Entamoeba histolytica.
Consult a registered physician before use.
Pharmacology
Nitazoxanide is a synthetic antiprotozoal medication for oral use. Its effectiveness is attributed to the interference with the Pyruvate Ferredoxin Oxido Reductase (PFOR) enzyme-dependent electron transfer reaction, crucial for the anaerobic energy metabolism of protozoa. Both Nitazoxanide and its active metabolite, tizoxanid, inhibit the growth of sporozoites and oocysts of Cryptosporidium parvum and trophozoites of Giardia lamblia.
Dosage & Administration
- Ages 1-3 years: 1 teaspoon (5 ml) suspension every 12 hours for 3 days.
- Ages 4-11 years: 2 teaspoons (10 ml) suspension every 12 hours for 3 days.
- Ages 12 years and above: 5 teaspoons (25 ml) suspension or 1 tablet every 12 hours for 3 days.
It is recommended to take with food.
Consult a registered physician before use.
Interaction
Nitazoxanide is highly protein-bound in plasma. Exercise caution when administering it alongside other highly protein-bound medications with a narrow therapeutic index.
Contraindications
Contraindicated in individuals with known hypersensitivity to Nitazoxanide or any components of the formulation.
Side Effects
Common side effects include abdominal pain, vomiting, and headache, usually mild and temporary. Rare side effects may include nausea, anorexia, flatulence, increased appetite, enlarged salivary glands, elevated creatinine and SGPT levels, pruritus, rhinitis, sweating, dizziness, and discolored urine.
Pregnancy & Lactation
Nitazoxanide is classified as a US FDA pregnancy category B drug. There are no sufficient and controlled studies in pregnant women, so it should be used during pregnancy only when absolutely necessary. Nitazoxanide is excreted in human milk; therefore, caution is advised during lactation.
Precautions & Warnings
Use Nitazoxanide cautiously in patients with hepatic and biliary disorders, as well as those with renal conditions.
Therapeutic Class
- Anti-diarrheal Antiprotozoal
Storage Conditions
Store in a dry place away from light and heat. Keep out of reach of children.
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