Myrox

Indications:

Myrox is recommended for the treatment of:

• Productive cough
• Acute and chronic inflammation of the upper and lower respiratory tracts with thick mucus, including conditions like acute and chronic bronchitis
• Inflammatory disorders of the rhinopharyngeal tract (such as laryngitis, pharyngitis, sinusitis, and rhinitis) accompanied by thick mucus
• Asthmatic bronchitis and bronchial asthma with excessive mucus production
• Bronchiectasis
• Chronic pneumonia and other related conditions

Note: Always use Myrox as per the guidance of a registered healthcare professional.

Pharmacology:

Ambroxol, the active metabolite of bromhexine, has a more potent bronchosecretolytic effect than its precursor, bromhexine. It enhances mucus flow in the respiratory system by hydrating and thinning the mucus, which eases expectoration and helps alleviate shortness of breath (dyspnea). Ambroxol also stimulates the production of surfactant phospholipids in alveolar cells, lowering surface tension in the alveoli for better lung function. Additionally, it reduces bronchial hyperactivity and has anti-inflammatory properties by inhibiting cellular cytokines and arachidonic acid metabolites. In COPD patients, Ambroxol helps improve airway patency and overall lung health.

Dosage & Administration:

The usual dosage is as follows (preferably after meals):

Pediatric Drops:

• 0-6 months: 0.5 ml twice daily
• 6-12 months: 1 ml twice daily
• 1-2 years: 1.25 ml twice daily

Syrup:

• 2-5 years: 2.5 ml (1/2 teaspoonful) 2-3 times daily
• 5-10 years: 5 ml (1 teaspoonful) 2-3 times daily
• 10 years and adults: 10 ml (2 teaspoonfuls) 3 times daily

Sustained Release Capsule:

• Adults and children over 12 years: 1 capsule once daily

Note: Always follow the advice of a registered healthcare professional when using this medicine.

Interaction:

Myrox should not be taken together with antitussives like codeine, as the liquefied phlegm may not be effectively expelled.

Contraindications:

Myrox is contraindicated in individuals with a known allergy to Ambroxol or Bromhexine.

Side Effects:

Some potential gastrointestinal side effects include occasional epigastric pain or a sensation of stomach fullness. Rare allergic reactions, such as skin rashes, urticaria, or angioneurotic edema, may occur.

Pregnancy & Lactation:

Studies on teratogenicity and fetal toxicity have shown no harmful effects of Ambroxol. However, it is advised to avoid using Myrox during pregnancy, particularly in the first trimester. The safety of Ambroxol during breastfeeding has not been established.

Precautions & Warnings:

Use Myrox with caution in patients with gastric ulcers, duodenal ulcers, or convulsive disorders. It should also be used carefully in individuals with liver or kidney insufficiency.

Therapeutic Class:

Cough expectorants & mucolytics

Storage Instructions:

• Store in a dry place, away from direct sunlight.
• Keep the temperature below 30°C.
• Keep out of reach of children.