Micosone Cream

Indications for Use

• Topical treatment for inflamed dermatoses with coexisting infection, such as intertrigo and infected eczema.
• Effective for various forms of eczema and dermatitis, including atopic eczema, irritant contact eczema, allergic contact eczema, and seborrheic eczema, including cases associated with acne.
• Also indicated for intertriginous eczema, including perianal and genital dermatitis.
• Miconazole targets dermatophytes and pathogenic yeasts (e.g., Candida spp.), as well as several gram-positive bacteria, such as Streptococcus and Staphylococcus.

Use only as directed by a healthcare professional.

Pharmacology

• Miconazole is a broad-spectrum azole antifungal that works by disrupting ergosterol synthesis in fungal cell membranes, causing cell death. It is effective against superficial candidiasis, dermatophytosis, pityriasis versicolor, seborrheic dermatitis, and other skin infections. It also targets Aspergillus spp., Cryptococcus neoformans, Pseudallescheria boydii, and certain gram-positive bacteria like Staphylococci and Streptococci.
• Hydrocortisone is a synthetic glucocorticoid known for its anti-inflammatory and anti-pruritic properties. It reduces skin inflammation by inhibiting the release of chemicals responsible for causing irritation and redness. When applied topically, hydrocortisone is absorbed into the skin to help alleviate swelling and discomfort.

Dosage & Administration

• Apply a thin layer of the cream to the affected area 2 to 4 times daily for 1 to 2 weeks. Gently rub the cream into the skin until fully absorbed.
• Continue treatment for at least one week after the symptoms disappear to ensure complete resolution of the infection.
• The dosage is the same for both adults and children.

Always follow the advice of a registered healthcare professional.

Drug Interactions

• Amphotericin B may antagonize the activity of Miconazole, reducing its effectiveness.

Contraindications

• Do not use if you are hypersensitive to Miconazole or any of the product’s components.
• Not recommended for use during pregnancy or lactation without a doctor’s advice.

Side Effects

• Rare cases of local sensitivity may occur.
• Long-term use may potentially reduce the natural production of hormones by the adrenal glands.

Pregnancy & Lactation

• High doses of corticosteroids in pregnant animals have been linked to fetal development abnormalities.
• Topical steroids should only be used during pregnancy if absolutely necessary, and under the guidance of a healthcare professional.
• Hydrocortisone is excreted in breast milk, so use during lactation should be avoided unless recommended by a doctor.

Precautions & Warnings

• Prescription only: This medication should only be used under the supervision of a licensed healthcare provider.
• Keep out of reach of children.
• Use with caution in children and elderly patients for long-term treatment. Always consult a doctor before prolonged use.

Therapeutic Class

• Hydrocortisone & Combined Preparations
• Topical Anti-inflammatory & Antifungal Treatments

Storage Conditions

• Store at a temperature below 30°C, away from light and moisture.
• Keep out of reach of children.