Imotil

10.00৳ Strip

  • Imotil is active ingredient, Loperamide Hydrochloride, interacts with cholinergic and noncholinergic neuronal mechanisms in the intestine to inhibit peristaltic activity.
  • Administration is typically oral, with absorption occurring at a modest rate and peak serum levels reached around 4 hours after ingestion.
  • Dosage varies based on age and condition, with caution advised for those with severe hepatic disturbance.
  • Side effects may include abdominal pain, dry mouth, dizziness, fatigue, and skin rashes.
  • Imotil should be stored in a cool, dry place protected from light and kept out of reach of children.
Brand

Square Pharmaceuticals PLC

Generics

Loperamide Hydrochloride

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Description

Indications

Imotil is prescribed for the following conditions:

  • Acute diarrhea
  • Chronic diarrhea
  • Abdominal cramps associated with diarrhea
  • Crohn’s disease
  • Postgastric surgery
  • Ulcerative colitis

Pharmacology

Loperamide Hydrochloride, the active ingredient in Imotil, works by inhibiting the peristaltic activity of the intestinal smooth muscles. It interacts with cholinergic and noncholinergic neuronal mechanisms, reducing propulsive peristalsis and increasing intestinal transit time. This medication binds to opiate receptors in the gut wall, thereby decreasing electrolyte and fluid secretion in the intestine. Loperamide Hydrochloride also enhances the tone of the anal sphincter.

Dosage & Administration

  • For acute diarrhea in adults: Start with 2 capsules followed by 1 capsule after each loose stool, not exceeding 8 capsules daily.
  • For chronic diarrhea in adults: Take 2-4 capsules daily in divided doses, adjusted based on severity.
  • Children’s dosage varies depending on age and severity, following physician’s advice.

Interaction

Currently, there are no available interaction data for Imotil.

Contraindications

  • Hypersensitivity to the drug
  • Patients who should avoid constipation
  • Imotil should not be used alone in cases of acute dysentery with blood in stool and elevated body temperature.

Side Effects

Common side effects may include abdominal pain, dry mouth, dizziness, fatigue, and skin rashes.

Pregnancy & Lactation

Safety during pregnancy has not been established. Caution is advised when administering Imotil to nursing mothers due to minimal secretion in breast milk.

Precautions & Warnings

Exercise caution in cases of severe hepatic disturbance when using Imotil.

Overdose Effects

Overdosing on Imotil may lead to constipation, CNS depression, and nausea.

Therapeutic Class

Imotil belongs to the therapeutic class of anti-diarrheal and anti-motility drugs.

Storage Conditions

Store Imotil in a cool, dry place away from light, and out of reach of children.

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