Indications
This medication is used to treat infections caused by susceptible organisms, particularly Staphylococcus bacteria. Common conditions include:
- Osteomyelitis
- Septicemia
- Endocarditis
- Superinfected cystic fibrosis
- Pneumonia
- Skin and soft tissue infections
- Infections from surgical or traumatic wounds
Note: Always follow the advice of a registered healthcare professional before taking this medication.
Pharmacological Action
Fusidic acid works by inhibiting bacterial protein synthesis. It does this by disrupting the transfer of amino acids from aminoacyl-tRNA to protein chains on the ribosomes, thereby preventing bacterial growth and replication.
Dosage & Administration
- Adults: Take 250-500 mg every 8 hours
- Skin & Soft Tissue Infections: Take 250 mg twice daily
- Important Reminder: Always consult a registered healthcare professional for proper dosing instructions.
Drug Interactions
Fusidic acid may interact with other medications metabolized by the CYP450 isoenzymes. Always inform your doctor of any other medications you are currently taking.
Contraindications
This medication should not be used by individuals who have a known hypersensitivity to fusidic acid.
Potential Side Effects
Common side effects may include:
- Gastrointestinal disturbances such as dyspepsia, nausea, vomiting, epigastric pain, and anorexia
- Jaundice or changes in liver function
If you experience any of these, contact your healthcare provider promptly.
Pregnancy & Lactation
No specific data is available regarding the safety of fusidic acid during pregnancy and lactation. Always consult your doctor before use if you are pregnant or breastfeeding.
Precautions & Warnings
Use with caution in individuals with:
- Liver impairment
- Biliary obstruction or disease
Periodic liver function tests are recommended for patients on long-term or high-dose oral treatment.
Avoid use during the third trimester of pregnancy. Not recommended for premature infants, or neonates with jaundice, acidosis, or serious illness.
Therapeutic Class
Antibiotic – Other
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