Cyclopan

Indications

Cyclopan is recommended for the following conditions:

• Irritable Bowel Syndrome (IBS) and other functional bowel disorders
• Urinary Incontinence resulting from unstable detrusor muscle activity
• Infantile Colic
• Gastrointestinal Tract (GIT) Spasms
• Colicky Abdominal Pain
• Diverticulitis
• Abdominal Colic

Always use Cyclopan as directed by a registered healthcare professional.

Pharmacological Information

Dicycloverine hydrochloride is classified as an antispasmodic and anticholinergic (antimuscarinic) medication. Its chemical structure is [Bicyclohexyl-]1-carboxylic acid, 2-(diethylammo) ethyl ester, hydrochloride. Dicycloverine effectively alleviates smooth muscle spasms in the gastrointestinal tract. The injectable form of Dicycloverine HCl is a sterile, pyrogen-free aqueous solution intended for intramuscular use only (not for intravenous administration).

The drug acts on specific cholinergic (muscarinic) receptors found in the involuntary muscles lining the gut. By binding to these receptors, Dicycloverine inhibits certain bodily chemicals from interacting with them, leading to relaxation of the gut muscles and relief from colic pain caused by muscle contractions and spasms.

Dosage and Administration

For oral dosage forms:

• Adults: 10 to 20 mg taken three times daily.
• Children over 6 months: 5 to 10 mg taken three times daily.

For injectable dosage form:

• Adults: Administered via intramuscular injection only (not for intravenous use). The recommended dosage is 80 mg daily, divided into four equal doses.

It is advisable to initiate oral Dicycloverine Hydrochloride treatment as soon as possible, and the intramuscular form should not be administered for longer than 1 to 2 days.

Note: Dosing for children should be determined by a healthcare provider.

Always use Cyclopan as directed by a registered healthcare professional.

Side Effects

Possible side effects may include:

• Insomnia
• Mydriasis (pupil dilation)
• Cycloplegia (inability to focus)
• Increased ocular pressure
• Urinary hesitancy
• Palpitations
• Dyspnea (difficulty breathing)

Pregnancy and Lactation

Pregnancy Category B: Dicycloverine has shown no teratogenic or embryotoxic effects in animal studies. However, like all medications, it should only be used during pregnancy if absolutely necessary. There is limited data on the excretion of this drug in breast milk; caution is advised when administered to nursing mothers.

Precautions and Warnings

Dicycloverine should be used cautiously in patients with the following conditions:

• Autonomic neuropathy
• Hepatic or renal disease
• Ulcerative colitis
• Coronary heart disease
• Congestive heart failure
• Cardiac tachyarrhythmia
• Hiatal hernia
• Known or suspected prostatic hypertrophy

Overdose Effects

While toxic reactions are rare, overdose symptoms may include:

• Headache
• Nausea
• Vomiting
• Blurred vision
• Dilated pupils
• Hot, dry skin
• Dizziness
• Dry mouth
• Difficulty swallowing
• Central nervous system stimulation

Therapeutic Classification

Class: Anticholinergics (antimuscarinics) / Antispasmodics

Storage Instructions

Store at temperatures below 30°C, away from light and moisture. Keep out of reach of children.