Citicol 500

500.00৳ Strip

  • Citicol is a CNS stimulant that enhances recovery from ischemic strokes, alleviates cerebral insufficiency, and manages cognitive dysfunction in Alzheimer’s and Parkinson’s disease.
  • Contains Citicoline, which supports neuronal repair, boosts neurotransmitter levels, and provides neuroprotection.
  • Available in oral and injectable forms, Citicol improves cognitive function and motor skills, offering a versatile treatment option.
Brand

Beximco Pharmaceuticals Ltd

Type

Tablet

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Description

Indications

Citicol is used for:

  • Cerebrovascular Disease: Facilitates recovery from ischemia due to stroke, enhancing consciousness and motor function. Initiating treatment within 24 hours post-stroke increases the likelihood of complete recovery within three months.
  • Cerebral Insufficiency: Alleviates symptoms like dizziness, memory loss, poor concentration, and disorientation resulting from head trauma or brain injury.
  • Cognitive Dysfunction: Effective in treating cognitive decline associated with degenerative diseases such as Alzheimer’s.
  • Parkinson’s Disease: Acts as a co-therapy to support management of Parkinson’s disease.

Pharmacology

Citicoline, a natural substance, is crucial for synthesizing cell membrane phospholipids. When taken orally, it is metabolized into choline and cytidine, which cross the blood-brain barrier and recombine into Citicoline in the CNS. It promotes the repair of neuronal membranes, boosts neurotransmitter levels (like acetylcholine and dopamine), and offers neuroprotection during hypoxic and ischemic conditions. Citicoline also improves learning and memory, and inhibits Phospholipase A2 to prevent cell death.

Dosage & Administration

  • Oral:
    • Acute Stroke Treatment: 500-2000 mg per day, starting within 24 hours of stroke onset.
    • Cognitive Decline Post-Stroke: 1000-2000 mg daily.
    • Chronic Cerebrovascular Disease: 1000 mg daily, divided doses, with or between meals.
  • Injection:
    • Administer 1-2 injections daily, adjusted based on severity.
    • Can be given intramuscularly (IM) or intravenously (IV) over 3-5 minutes.
  • Geriatric Use: No dosage adjustment needed.

Interaction

Citicoline may enhance the effects of levodopa, carbidopa, and entacapone. Avoid co-administration with meclophenoxate-containing products.

Contraindications

Not suitable for patients with hypertonia of the parasympathetic nervous system.

Side Effects

May cause temporary stimulation of the parasympathetic system and occasional hypotension.

Pregnancy & Lactation

No well-controlled studies are available for pregnant or lactating women. Use only if the benefits outweigh potential risks.

Precautions & Warnings

May cause dizziness or drowsiness; avoid operating machinery. Monitor for hypotension and treat if necessary with corticosteroids or sympathomimetics. Administer slowly in cases of persistent intracranial hemorrhage, and avoid alcohol during treatment.

Therapeutic Class

CNS Stimulants

Storage Conditions

Store below 30°C, away from light and moisture. Keep out of reach of children.

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