Candirox Nail Lacquer

Indications

Candirox Nail Lacquer is a topical solution designed for treating mild to moderate nail fungus (onychomycosis) in fingernails and toenails for immunocompetent patients. It specifically targets infections caused by Trichophyton rubrum and is recommended only for cases without lunula involvement.
নির্দেশিত ঔষধটি শুধুমাত্র রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ব্যবহার করুন

Pharmacology

Ciclopirox, the active ingredient in Candirox Nail Lacquer, is a synthetic antifungal agent. This clear, colorless to lightly yellow solution is applied to the fingernails, toenails, and adjacent skin. Unlike azole-based antifungal drugs, the exact action mechanism of Ciclopirox is not fully understood. However, it’s believed to inhibit certain fungal enzymes, such as catalase and peroxidase, thereby disrupting various cellular metabolic processes within the fungus.

Dosage & Administration

1. Prior to treatment, use nail clippers or files to remove any loose nail material. Patients with diabetes or numbness in fingers or toes should consult a healthcare provider before trimming nails or removing nail material.
2. Apply Candirox Nail Lacquer daily to the entire nail plate (preferably at bedtime or eight hours before washing) using the provided applicator brush. If possible, also apply it to the underside of the nail and surrounding skin. Allow about 30 seconds to dry before wearing socks or stockings.
3. Apply a new coat daily over the previous application.
4. Once a week, remove Candirox Nail Lacquer with an alcohol pad or nail polish remover. Use scissors, clippers, or a nail file to remove as much damaged nail as possible.
5. Repeat steps 2–4 consistently for 6 to 48 weeks, as directed.
   নির্দেশিত ঔষধটি শুধুমাত্র রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ব্যবহার করুন

Interaction

There are no studies on whether Candirox reduces the effectiveness of oral antifungal medications for onychomycosis. Therefore, concurrent use of Candirox 8% solution and systemic antifungal agents is not advised.

Contraindications

Candirox Nail Lacquer should not be used by individuals with a known hypersensitivity to any of its ingredients.

Side Effects

Possible side effects include redness or burning at the application site and minor changes in nail shape or color. Serious allergic reactions to Candirox are rare.

Pregnancy & Lactation

Candirox is classified as Pregnancy Category B. While no comprehensive studies exist on topical ciclopirox in pregnant women, it should only be used during pregnancy if the potential benefits outweigh the risks to the fetus. It’s unknown if this drug is excreted in breast milk; therefore, caution is advised when administering it to nursing mothers.

Precautions & Warnings

If signs of sensitivity or chemical irritation occur, discontinue use. Care should be taken in patients with insulin-dependent diabetes or diabetic neuropathy, especially when nail removal is needed. Candirox Nail Lacquer is for external use only, specifically for nails and adjacent skin. Avoid contact with eyes, mouth, or vaginal areas.

Use in Special Populations
For Children: Safe for use in children 12 years and older. No clinical trials have been conducted specifically in pediatric patients.

Therapeutic Class

Other preparations

Storage Conditions

Store below 30°C. Protect Candirox Nail Lacquer from heat, keep the bottle tightly closed, and away from light and children.