Dixar Plus

Indications

Dixar Plus provides temporary relief from symptoms caused by common colds, hay fever (allergic rhinitis), or upper respiratory allergies, including:

• Cough due to mild throat or bronchial irritation
• Runny nose
• Sneezing
• Nasal and throat itching
• Itchy, watery eyes
• Nasal congestion
• Swelling in nasal passages

Use medication as prescribed by a registered physician.

Pharmacology

Dixar Plus is a combination of an antitussive, decongestant, and antihistamine.

• Dextromethorphan: A non-narcotic cough suppressant that acts centrally on the cough center in the medulla. Unlike morphine, it lacks analgesic, addictive, or sedative properties.
• Phenylephrine: A nasal decongestant that reduces nasal and sinus congestion by shrinking blood vessels. It also aids in draining fluid from the inner ear.
• Triprolidine: A competitive H1-receptor antagonist that alleviates histamine-related symptoms. It has mild sedative properties and may cause drowsiness.

Dosage

• Adults & children 12 years and older: 5 ml (1 teaspoon) every 4 hours, or as directed by a doctor.
• Children 6–12 years: 2.5 ml (½ teaspoon) every 4 hours, or as directed by a doctor.
• Children 2–6 years: Use cautiously and only under medical supervision.
• Children under 2 years: Not recommended.

Use medication as prescribed by a registered physician.

Administration

• Can be taken with or without food. If it causes stomach upset, take with food.
• Measure doses accurately using the provided measuring device.

Use medication as prescribed by a registered physician.

Drug Interactions

Avoid combining Dixar Plus with MAO inhibitors (e.g., phenelzine, rasagiline, or selegiline), as this can result in severe and potentially fatal interactions. Ensure a gap of at least two weeks before starting Dixar Plus after discontinuing MAO inhibitors. Exercise caution when used with:

• Antihistamines (e.g., diphenhydramine cream or spray)
• Antispasmodics
• Beta blockers
• Parkinson’s medications
• Tricyclic antidepressants
• Anti-seizure drugs
• Sedatives or narcotic pain relievers

Contraindications

Do not use Dixar Plus in patients with:

• Liver disease
• Acute asthma attacks
• Severe hypertension or coronary artery disease
• Hypersensitivity to phenylephrine, dextromethorphan, or other components

Side Effects

Common side effects include drowsiness, mild constipation, and gastrointestinal discomfort. Rare side effects may include:

• Transient hypertension
• Dry mouth
• Restlessness or palpitations
• Allergic reactions (rash, chest tightness)
• Psychosis, hallucinations, or blood abnormalities

Pregnancy & Lactation

Avoid using this medication during pregnancy and breastfeeding unless prescribed by a doctor.

Precautions

• Dixar Plus may cause drowsiness; avoid driving or operating heavy machinery.
• Refrain from alcohol consumption during treatment.
• Use cautiously in patients with epilepsy, glaucoma, hypertension, diabetes, or peptic ulcers.
• Seek medical advice if symptoms persist for over a week or if accompanied by a high fever.

Overdose Effects

Overdose may lead to respiratory depression, hallucinations, paranoia, or convulsions. Immediate medical attention is necessary.

• Phenylephrine overdose: May cause severe hypertension, reflex bradycardia, and require gastric lavage, alpha-receptor blockers (e.g., phentolamine), or atropine.
• Dextromethorphan overdose: Treat with sedatives like diazepam to manage nervous stimulation and convulsions.

Therapeutic Class

Combination cough suppressants

Storage Instructions

• Store in a cool, dry place away from light.
• Keep out of reach of children.