Calvimax Plus

Indications for Calvimax Plus

Calvimax Plus is recommended for:

• Preventing and treating osteoporosis
• Supporting healthy bone growth
• Ensuring proper heart, muscle, and nerve function
• Acting as a nutritional supplement
• Promoting bone development and regeneration
• Use during pregnancy and lactation
• Addressing deficiencies in Calcium, Vitamin D3, Magnesium, Zinc, Copper, Manganese, and Boron

Composition

Each film-coated tablet contains:

• Calcium Carbonate BP equivalent to 600 mg of elemental Calcium
• Vitamin D3 BP (Cholecalciferol) 200 IU
• Magnesium Oxide BP equivalent to 40 mg of Magnesium
• Manganese Sulfate Monohydrate BP equivalent to 1.8 mg of Manganese
• Cupric Oxide equivalent to 1 mg of Copper
• Boron Citrate equivalent to 250 mcg of Boron
• Zinc Oxide BP equivalent to 7.5 mg of Zinc

Each effervescent tablet contains:

• Calcium Carbonate BP equivalent to 600 mg of elemental Calcium
• Vitamin D3 BP (Cholecalciferol) 400 IU
• Magnesium Oxide BP equivalent to 40 mg of Magnesium
• Manganese Sulfate Monohydrate BP equivalent to 1.8 mg of Manganese
• Cupric Oxide equivalent to 1 mg of Copper
• Boron Citrate equivalent to 250 mcg of Boron
• Zinc Oxide BP equivalent to 7.5 mg of Zinc

Pharmacology

Proper nutrition is essential for preventing osteoporosis and other bone-related conditions. Key nutrients like Calcium, Magnesium, and Vitamin D3 are vital for bone health, as Vitamin D3 enhances Calcium absorption. Magnesium also contributes to bone strength. Recent studies highlight the importance of micronutrients such as Copper, Manganese, Zinc, and Boron in maintaining bone integrity, particularly in individuals with osteoporosis.

Dosage & Administration

• Adults: Take 1 film-coated tablet twice daily, preferably one in the morning and one in the evening, or as directed by a healthcare professional. It’s best to take with or shortly after meals, along with a full glass of water.
• Children (ages 3-7): 1 effervescent tablet daily.
• Children (ages 7 and older): 1 to 2 effervescent tablets daily.

Always consult a registered healthcare professional before use.

Interactions

Be cautious of hypercalcemia in patients on thiazide diuretics, which may reduce urinary calcium excretion. Monitor calcium levels in patients using digitalis or other cardiac glycosides, as calcium can interfere with their effects. Certain foods and medications can reduce calcium absorption; it’s recommended to space calcium intake at least four hours apart from these substances.

Contraindications

Absolute Contraindications: Hypercalcemia due to conditions like myeloma, bone metastasis, sarcoidosis, primary hyperparathyroidism, Vitamin D3 overdose, and severe renal failure. Hypersensitivity to any ingredients is also a contraindication.

Relative Contraindications: Osteoporosis related to prolonged immobility, renal stones, and severe hypercalciuria.

Side Effects

Calcium supplements can occasionally cause mild gastrointestinal issues, such as constipation, nausea, or diarrhea. Rarely, vitamin D3 may result in skin rashes. Long-term high-dose use can lead to hypercalciuria or hypercalcemia.

Pregnancy & Lactation

During pregnancy and lactation, treatment should be under medical supervision. Calcium and Vitamin D3 requirements increase during these periods, and supplementation should account for dietary sources. If both calcium and iron are required, take them at different times. Excessive Vitamin D3 can have teratogenic effects.

Precautions & Warnings

Patients with renal issues should be monitored closely for calcium levels and urinary excretion. Regular checks are essential for those with a history of renal stones or hypercalciuria. Monitor serum and urinary calcium levels during prolonged treatment, adjusting as necessary.

Overdose Effects

Overdosage may present symptoms such as nausea, vomiting, drowsiness, dry mouth, appetite loss, metallic taste, stomach cramps, diarrhea, headaches, and constipation.

Therapeutic Class

Specific combined mineral and vitamin preparations.

Storage Conditions

Store in a dry place away from light and heat. Keep out of reach of children.