Rynex Nasal Drop

Indications

Rynex is specifically formulated to alleviate nasal congestion resulting from acute or chronic rhinitis, the common cold, sinusitis, upper respiratory allergies, epistaxis, and hay fever. Additionally, it serves as a nasal decongestant for conditions like otitis media.
Usage should always align with the advice of a registered healthcare professional.

Pharmacology

Oxymetazoline Hydrochloride is an imidazoline derivative and sympathomimetic amine. It functions as a direct agonist at α-adrenoceptors while exhibiting no activity on β-adrenoceptors. As a topical agent for the nasal mucosa, it delivers rapid and prolonged vasoconstriction of the arterioles, which reduces blood flow and alleviates swelling of the mucosa. This mechanism enhances airflow and facilitates better drainage of the nasal sinuses.

Dosage

Oxymetazoline Nasal Spray:

• Adults and children (6 years and older): 2 to 3 sprays in each nostril twice daily for a duration of 3-5 days.
• Elderly: No dosage adjustment is necessary for elderly patients when used nasally.
• Children under 6 years: Not recommended for this age group.

Oxymetazoline Nasal Drops:

• Adults and children (6 years and older): 2 to 3 drops of 0.05% Nasal Drops in each nostril twice daily (morning and evening).
• Children (2-5 years): 2 to 3 drops of 0.025% Nasal Drops in each nostril twice daily (morning and evening).

Usage should always align with the advice of a registered healthcare professional.

Administration

How to Use the Nasal Spray:

1. Gently shake the bottle and remove the dust cover.
2. Position your forefinger and middle finger on either side of the nozzle, with your thumb supporting the bottom of the bottle. Press down until a fine spray is released. If using for the first time or after a week of non-use, pump the nasal applicator several times until a fine mist emerges.
3. Clear your nostrils by gently blowing your nose.
4. Close one nostril and insert the nasal applicator into the other. Tilt your head slightly forward and keep the spray upright. Inhale through your nose while pressing down firmly on the white collar of the applicator to release a spray.
5. Exhale through your mouth.
6. Repeat the above steps for the other nostril as needed.

Cleaning Instructions: The nasal spray should be cleaned weekly. Follow these steps:

1. Remove the dust cover.
2. Carefully detach the nasal applicator.
3. Wash both the applicator and dust cover in warm water.
4. Shake off excess water and allow to air dry in a normal environment; avoid applying direct heat.
5. Reattach the applicator to the bottle and secure the dust cover.

Usage should always align with the advice of a registered healthcare professional.

Interaction

Rynex loride Nasal Preparation should not be administered to patients undergoing treatment with MAO inhibitors or within 14 days of stopping such therapy.

Contraindications

This medication is contraindicated for individuals with cardiovascular diseases, hyperthyroidism, prostatic enlargement, angle-closure glaucoma, and those with hypersensitivity to any component of the product.

Side Effects

Occasionally, users may experience local irritation and dryness in the mouth and throat. Temporary discomfort such as burning, stinging, sneezing, or increased nasal discharge may also occur.

Pregnancy & Lactation

The safety of Oxymetazoline Hydrochloride Nasal Spray during pregnancy and breastfeeding has not been thoroughly established, but it is generally not considered hazardous during these periods.

Precautions & Warnings

Keep the spray away from the eyes. It should not be used for more than seven consecutive days without medical guidance. Frequent or prolonged use may lead to a recurrence or worsening of nasal congestion.

Overdose Effects

An overdose may cause local irritation and rebound congestion. Treatment should focus on symptomatic relief.

Therapeutic Class

Nasal Anti-histamine Preparations, Nasal Decongestants, and Other Nasal Preparations.

Storage Conditions

Store below 30°C in a dry environment, protected from light. Do not refrigerate or freeze. Keep out of reach of children.