Zymet Pro 325

Indications

Zymet Pro is prescribed for the management of various conditions, including:

• Chronic pancreatitis
• Cystic fibrosis (mucoviscidosis)
• Post-pancreatectomy (partial or complete)
• Total gastrectomy
• Steatorrhea
• Somatostatinoma
• Celiac disease
• Other pancreatic insufficiency-related disorders

Composition

Each enteric-coated tablet of Zymet Pro contains 325 mg of Pancreatin BP, delivering the following enzymatic activities:

• Amylase: 7800 units
• Protease: 455 units
• Lipase: 6500 units

Pharmacology

Zymet Pro is formulated with Pancreatin, an extract from mammalian pancreas enriched with essential enzymes such as Amylase, Protease, and Lipase. Designed to dissolve in the alkaline environment of the duodenum, it releases these active enzymes to aid digestion. Amylase breaks down dietary starches into maltose and other carbohydrates, Protease cleaves protein molecules into amino acids and peptides, and Lipase transforms dietary fats into fatty acids and monoglycerides. It efficiently converts starch and casein into soluble carbohydrates and proteoses, respectively, within 5 minutes, achieving significant digestion within 30 minutes.

Dosage & Administration

Take 2-3 tablets with a small amount of water, immediately before or during meals, or as directed by your healthcare provider.

Interactions

To prevent premature release of the medication, avoid using Zymet Pro concurrently with antacids, as they may disrupt the enteric coating.

Contraindications

Zymet Pro should not be used in individuals with a known hypersensitivity to Pancreatin.

Side Effects

Common side effects may include gastrointestinal issues such as nausea, vomiting, and abdominal discomfort. Infants may experience soreness in the buccal or perianal areas. Allergic reactions like sneezing, lacrimation, or skin rashes have been reported.

Pregnancy & Lactation

Administer Pancreatin to pregnant women only if absolutely necessary. Its excretion in human milk is unknown; hence, caution is advised when administering this medication to breastfeeding mothers.

Precautions & Warnings

Use with caution in patients allergic to animal proteins.

Overdose Effects

An excessive dose may cause a laxative effect. Systemic toxicity is not expected, but very high doses could lead to hyperuricemia and hyperuricosuria.

Therapeutic Class

Digestive Enzyme

Storage Conditions

Store in a cool, dry place away from light and out of reach of children.