Zolfin 100

Indications

Zolfin is prescribed to alleviate pain and reduce inflammation associated with various conditions including osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, toothaches, trauma, and lumbago.

Pharmacology

Zolfin contains Aceclofenac, a non-steroidal anti-inflammatory drug (NSAID) known for its potent anti-inflammatory and analgesic effects. Aceclofenac works by inhibiting cyclooxygenase (COX), an enzyme critical in the synthesis of prostaglandins, which are compounds involved in inflammation and pain. Following oral administration, Aceclofenac is rapidly and thoroughly absorbed in its active form.

Dosage & Administration

• Extended Release Tablets: For adults, the standard dosage is one 200 mg tablet per day, or as directed by your healthcare provider.
• Film-Coated Tablets: For adults, the recommended dose is 100 mg twice daily.

Always follow your doctor’s advice when taking medication.

Drug Interactions

While no major drug interactions have been reported, monitoring is advised when used concurrently with:

• Lithium and Digoxin: May elevate plasma levels of these substances.
• Diuretics: May affect the efficacy of diuretics.
• Anticoagulants: May potentiate the effects of blood thinners.
• Methotrexate: May increase methotrexate plasma levels.

Contraindications

Zolfin should not be used by individuals with known hypersensitivity to Aceclofenac or those who experience asthma attacks triggered by aspirin or other NSAIDs.

Side Effects

Common side effects include those typical of NSAIDs, such as gastrointestinal discomfort. Consult your healthcare provider for a full list of potential side effects.

Pregnancy & Lactation

Use of Aceclofenac during pregnancy and breastfeeding is generally advised against unless the benefits outweigh potential risks to the fetus or infant.

Precautions & Warnings

Use Zolfin with caution in individuals with active or suspected peptic ulcers, gastrointestinal bleeding, severe hepatic impairment, or cardiac and renal conditions. Caution is also recommended for those experiencing dizziness or urticaria.

Use in Special Populations

There is limited clinical data on the safety and efficacy of Zolfin in children.

Therapeutic Class

• Osteoarthritis Medications
• Rheumatoid Arthritis Treatments
• Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

Storage Conditions

Store in a cool, dry place away from direct light and heat. Keep out of reach of children.