Vitabion

Indications

Vitamin B1, B6, and B12 tablets are designed to address deficiencies in these essential vitamins. They are effective in treating various conditions, including:

• Polyneuropathy of different origins, such as alcoholic or toxic neuropathies
• Neuritis and Neuralgia
• Cervical Syndrome
• Shoulder-arm Syndrome
• Lumbago and Sciatica
• Myalgia
• Intercostal Neuralgia
• Herpes Zoster
• Trigeminal Neuralgia
• Supportive care for facial paresis

Always consult a registered healthcare professional before using this medication.

Composition

Each film-coated tablet contains:

• Vitamin B1 (Thiamine Mononitrate): 100 mg
• Vitamin B6 (Pyridoxine Hydrochloride): 200 mg
• Vitamin B12 (Cyanocobalamin): 200 mcg

Each 3 ml ampoule includes:

• Thiamine Hydrochloride (Vitamin B1): 100 mg
• Pyridoxine Hydrochloride (Vitamin B6): 100 mg
• Cyanocobalamin (Vitamin B12): 1000 mcg

Pharmacology

Vitamin B1 is crucial for converting carbohydrates, fatty acids, and amino acids into energy, promoting healthy nerve function, enhancing mood, and supporting heart health. Vitamin B6 is vital for red blood cell formation, protein synthesis, neurotransmitter production (such as serotonin), and preventing cardiovascular diseases and strokes. Additionally, it helps alleviate depression and insomnia. Vitamin B12 is essential for cellular replication, red blood cell production, and preventing anemia. It also reduces symptoms of nerve pain, numbness, and tingling, while lowering the risk of heart disease.

These vitamins are effectively absorbed when taken orally and are distributed throughout the body, including in breast milk. Thiamine primarily exists as diphosphate within cells, with excess amounts excreted in urine. Pyridoxine and its derivatives are also well-absorbed and converted into active forms, stored mainly in the liver, and excreted as inactive metabolites.

Dosage & Administration

Tablets: Take 1-3 tablets daily or as directed by a healthcare professional.

Injection:

• For severe cases: Administer 1 injection daily until acute symptoms improve or as advised by a physician.
• For mild cases: Administer 1 injection 2-3 times weekly, preferably via intramuscular injection.

Use in children: There is limited information regarding the use of this medication in pediatric patients. Always consult a healthcare professional before use.

Interactions

Currently, no drug interactions have been reported.

Contraindications

This formulation is contraindicated for patients undergoing levodopa therapy or those with hypersensitivity to any of its components.

Side Effects

Generally well-tolerated, but allergic reactions may occur in some individuals.

Pregnancy & Lactation

While the oral tablet is recommended, injections containing benzyl alcohol are not advised during pregnancy or lactation.

Precautions & Warnings

Cyanocobalamin should not be administered to patients with subacute degeneration of the spinal cord or optic neuropathies associated with elevated plasma cyanocobalamin levels.

Overdose Effects

No overdose symptoms are expected with the recommended dosage. In case of overdose, provide symptomatic and supportive treatment.

Therapeutic Class

Specific combined vitamin preparations.

Storage Conditions

Keep out of reach of children. Store in a cool, dry place below 25°C, away from light.