Urikal 100ml

Indications

Urikal is recommended for the following conditions:

• Relief of discomfort associated with urinary tract infections (UTIs)
• Prevention of kidney stones
• Use alongside uricosuric agents to prevent gout
• Management of acidosis resulting from kidney diseases

Always consult a registered physician before taking any medication.

Pharmacology

Urikal contains a blend of Potassium Citrate and Citric Acid in an oral solution, designed as a stable and pleasant-tasting systemic alkalizer. Upon absorption, Potassium Citrate is converted to Potassium Bicarbonate, functioning as a systemic alkalizer. This formulation effectively alkalinizes urine without inducing systemic alkalosis at recommended doses. It is highly palatable and well-tolerated, even with extended use. Additionally, Potassium Citrate does not interfere with gastric juices or digestion.

Dosage & Administration

For relief from urinary tract infections:

• Adults and children over 6 years: Take 10 ml three times daily, diluted in one glass of water.
• Children aged 1-6 years: Take 5 ml three times daily, diluted in half a glass of water.

To prevent kidney stones, gout (in conjunction with uricosuric agents), and manage acidosis due to kidney conditions:

• Adults: 10-15 ml four times daily (or as directed by a physician), diluted in one glass of water.
• Pediatric patients: 5-10 ml four times daily (or as directed by a physician), diluted in half a glass of water.

Always consult a registered physician before taking any medication.

Interactions

Concurrent use of potassium-containing medications, potassium-sparing diuretics, angiotensin-converting enzyme (ACE) inhibitors, or cardiac glycosides may increase the risk of toxicity.

Contraindications

Urikal should not be used in patients with severe renal impairment, oliguria, azotemia, untreated Addison’s disease, acute dehydration, severe myocardial damage, or hyperkalemia of any origin.

Side Effects

This solution is typically well tolerated and does not cause significant side effects when taken at recommended doses by patients with normal renal function and urinary output. However, caution is advised for individuals with abnormal renal function to prevent hyperkalemia or alkalosis. Symptoms of potassium intoxication may include lethargy, weakness, mental confusion, tingling sensations in extremities, and other manifestations linked to elevated serum potassium levels.

Pregnancy & Lactation

Currently, there is no available data regarding the use of Urikal during pregnancy or lactation.

Precautions & Warnings

Use this solution cautiously in patients with low urinary output. Ensure it is adequately diluted with water to reduce the risk of gastrointestinal injury associated with concentrated potassium salt preparations; ideally, take each dose after meals. High doses may lead to hyperkalemia and alkalosis, particularly in patients with renal disease.

Overdose Effects

In individuals with normal potassium excretion mechanisms, oral potassium salts rarely cause serious hyperkalemia. However, in patients with impaired excretory functions, hyperkalemia can occur. Immediate treatment is essential if hyperkalemia is detected, as it can reach lethal levels within hours. Management includes:

1. Removing potassium-containing foods and medications from the diet.
2. Administering intravenous dextrose solution (10-25%) at a rate of 300-500 ml/hr, containing 10 units of insulin per 20 grams of dextrose.
3. Utilizing exchange resins, hemodialysis, or peritoneal dialysis as necessary.

Therapeutic Class

• Prevention of recurrent kidney stone formation
• Urinary alkalinizing agent

Storage Conditions

Store below 30°C, protected from light and moisture. Keep out of reach of children.