Indications
Topicort exhibits anti-inflammatory, immunosuppressant, and antimitotic actions, making it effective in various dermatological conditions. It is indicated for primary irritant dermatitis, contact allergic dermatitis, eczema (atopic, infantile, discoid, stasis), seborrheic dermatitis, lichen simplex, pruritus ani, flexural psoriasis, and various skin irritations, itching, and rashes caused by insect bites, minor burns, or sunburn.
Pharmacology
Hydrocortisone, the active ingredient, binds to cytosolic glucocorticoid receptors, leading to modulation of gene expression and inhibition of inflammatory mediators like prostaglandins and leukotrienes. It suppresses immune responses and diminishes inflammatory events, including cell adhesion, chemotaxis, and release of inflammatory mediators.
Dosage & Administration
Apply a small quantity of Hydrocortisone Acetate to the affected area 2 or 3 times daily as directed by a healthcare professional.
Contraindications
Contraindicated in cases of bacterial, viral, or fungal infections, skin ulcers, and hypersensitivity to the preparation.
Side Effects
Generally well-tolerated, but if signs of hypersensitivity occur, discontinue use.
Pregnancy & Lactation
Limited evidence for safety during pregnancy; avoid extensive use. Unlikely to reach breast milk in significant levels.
Precautions & Warnings
Avoid long-term continuous use in infants and children to prevent adrenal suppression. Prolonged application to the face should be avoided.
Overdose Effects
Acute overdosage is rare, but chronic misuse may lead to hypercorticism symptoms; discontinue use in such cases.
Therapeutic Class
Belongs to the category of other topical corticosteroids.
Storage Conditions
Store in a cool, dry place, away from light, and out of reach of children.
Brand
Generics
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