Ticamet HFA 250

Indications

Sultolin Inhaler is recommended for the regular treatment of asthma when a combination product (long-acting β2-agonist and inhaled corticosteroid) is deemed suitable. It’s prescribed for patients who aren’t adequately controlled with inhaled corticosteroids alone or for those already well-controlled on both inhaled corticosteroid and long-acting β2-agonist.

Pharmacology

Salmeterol Xinafoate, a selective long-acting beta-2 agonist, and Fluticasone Propionate, a corticosteroid with predominant glucocorticoid activity, constitute Sultolin Inhaler. While Salmeterol protects against symptoms, Fluticasone Propionate improves lung function and prevents asthma exacerbations. This combination offers a more convenient regimen for patients requiring concurrent β-agonist and inhaled corticosteroid therapy.

Dosage

For adults and adolescents aged 12 years and older, the recommended dosage is 2 puffs of Salmeterol (25 µg) and Fluticasone Propionate (50, 125, or 250 µg) twice daily. Children aged 4 to 12 years should take 2 puffs of Salmeterol (25 µg) and Fluticasone Propionate (50 µg) twice daily.

Administration

Effective inhaler use is crucial for optimal medication delivery. Follow these steps for proper administration: (Steps included here)

Interaction

Avoid concomitant use of Sultolin with non-selective β-blockers in asthma patients unless absolutely necessary. Clinically significant drug interactions are unlikely due to low plasma concentrations achieved after inhaled dosing. However, caution is advised when co-administering known strong CYP3A4 inhibitors.

Contraindications

Sultolin Inhaler is contraindicated in patients with a history of hypersensitivity to salmeterol xinafoate, fluticasone propionate, or any excipients. It should not be used as the primary treatment during acute episodes of asthma where intensive measures are required.

Side Effects

Adverse reactions associated with Sultolin Inhaler include those expected from both Salmeterol and Fluticasone Propionate. Common side effects and management strategies are discussed here.

Pregnancy & Lactation

Administration during pregnancy and lactation should be carefully considered, weighing the potential benefits against risks. Limited data are available regarding its use in human pregnancy and lactation.

Precautions & Warnings

Special precautions and warnings are provided for asthma patients, COPD patients, and the use of corticosteroids. Regular patient monitoring and dose adjustment are recommended.

Use in Special Populations

Special considerations for pediatric patients and the potential impact on growth velocity are discussed here.

Overdose Effects

Information on potential overdose effects and management strategies for both Salmeterol and Fluticasone Propionate is provided.

Therapeutic Class

Sultolin Inhaler belongs to the therapeutic class of long-acting selective β-adrenoceptor stimulants and respiratory corticosteroids.

Storage Conditions

Proper storage instructions for the pressurized canister are detailed here, emphasizing the need to avoid direct sunlight, heat, and puncturing.