Sultolin SR

Indications

Sultolin SR serves as a bronchodilator, prescribed for conditions such as asthma, chronic bronchitis, emphysema, and other ailments associated with airway obstruction.

Pharmacology

Salbutamol, a synthetic sympathomimetic agent, primarily exhibits beta-2 adrenergic activity. By stimulating beta-2-adrenergic receptors in bronchial smooth muscles, Salbutamol induces bronchodilation, leading to the relaxation of bronchial muscle fibers. This action results in enhanced pulmonary function, as evidenced by spirometric measurements.

Dosage & Administration

• Salbutamol tablet or syrup:
  • Children (2-6 years): 2.5 ml syrup, 3-4 times daily
  • Children (6-12 years): 5 ml syrup, 3-4 times daily
  • Adults: 2-4 mg tablet, 3-4 times daily, with a maximum single dose of 8 mg tablet.
• Salbutamol Respirator Solution:
  • Intermittent Administration: Dosage varies for adults and children, with careful attention to dilution and nebulization under medical guidance.
  • Continuous Administration: Administered via suitable nebulizer device, with oxygen supplementation if necessary.
• Salbutamol Inhalation Capsule:
  • Recommended doses for adults and children for relief of bronchospasm and managing intermittent episodes of asthma, with specific instructions for usage frequency and precautions.

Side Effects

Possible side effects of Sultolin SR may include fine tremors, palpitations, muscle cramps, tachycardia, headaches, and peripheral vasodilation, particularly with large doses.

Pregnancy & Lactation

Caution is advised regarding the use of Sultolin SR during pregnancy and lactation, with careful consideration of potential risks versus benefits.

Precautions & Warnings

Sultolin SR should be used cautiously in patients with certain medical conditions, including hyperthyroidism, cardiovascular disease, hypertension, and diabetes mellitus. Special care is warranted for patients on antihypertensive therapy.

Overdose Effects

Overdosage symptoms may include angina, headache, nausea, vomiting, and tremors. The preferred antidote for overdosage is a cardio-selective beta-blocking agent, although caution is advised in patients with a history of bronchospasm.

Therapeutic Class

Sultolin SR belongs to the therapeutic class of short-acting selective β2-adrenoceptor stimulants.

Storage Conditions

Store below 30°C, away from light and moisture, and ensure it is out of reach of children.