SQ-Mycetin

Indications

SQ-Mycetin treats ocular infections involving the conjunctiva and/or cornea caused by susceptible organisms such as Staphylococcus aureus, Streptococcus pneumoniae, E. coli, H. influenzae, Klebsiella/Enterobacter spp, Moraxella lacunata, and Neisseria species.

Pharmacology

Chloramphenicol, a broad-spectrum bacteriostatic antibiotic, inhibits bacterial protein synthesis by interfering with the transfer of activated amino acids from soluble RNA to ribosomes.

Dosage & Administration

For adults and children, instill 1 or 2 drops in the conjunctival sac 4-6 times daily for the initial 72 hours, then every 4 hours thereafter. Treatment should continue for about 7 days, with re-evaluation by a physician if extended beyond 3 weeks.

Interaction

Concurrent use of chymotrypsin may inhibit SQ-Mycetin’s efficacy.

Contraindications

Avoid use in individuals with a history of hypersensitivity to Chloramphenicol or any components of the preparation.

Side Effects

Short-term topical use typically avoids systemic adverse reactions. Commonly reported adverse effects include burning, stinging, conjunctival hyperemia, blood dyscrasia, and allergic or inflammatory reactions.

Pregnancy & Lactation

Use during pregnancy and lactation only when deemed essential by physicians due to uncertain safety profiles.

Precautions & Warnings

Reserve SQ-Mycetin for significant infections; avoid repeated or prolonged treatment to mitigate risks of blood dyscrasias.

Overdose Effects

Accidental ingestion is unlikely to cause toxicity due to the low antibiotic content.

Therapeutic Class

SQ-Mycetin falls under Ear Anti-Infectives & Antiseptics, Eye Anti-Infectives & Antiseptics, and Macrolides.

Storage Conditions

Store in a cool, dry place (between 2°C-8°C), shielded from light, and out of children’s reach. Avoid contact between the dropper tip and surfaces to prevent contamination. Discard after 30 days of opening.