Sopilax Oral Solution

Indications

Sopilax serves as a remedy for various conditions, including:

• Constipation stemming from any cause
• Alleviation of persistent and recurring constipation
• Bowel preparation prior to surgical procedures, childbirth, or radiological examinations.

Pharmacology

Sodium Picosulfate, a derivative of the triarylmethane group, functions as a stimulant laxative. Following oral intake, it undergoes activation by colonic bacteria, exerting its effects locally within the colon. The activated form stimulates nerve endings in the intestinal wall, leading to colonic peristalsis. This process promotes the accumulation of water and electrolytes in the colonic lumen, facilitating defecation, reducing transit time, and softening stool consistency. Additionally, rectal stimulation enhances motility and induces a sense of rectal fullness, potentially aiding in restoring the natural urge to defecate.

Dosage & Administration

Administered orally, Sopilax is ideally taken at bedtime to induce evacuation the following morning. It’s advisable to commence with the lowest effective dose, which may then be adjusted up to the maximum recommended dosage to achieve regular bowel movements. The maximum daily dosage should not be exceeded:

• 10 mg tablet dose:
  • Adults and children over 10 years of age: 5-10 mg per day.
  • Children aged 4-10 years: 2.5-5 mg per day.
• Oral Solution (5 mg/5 ml) dose:
  • Adults and children over 10 years of age: 5-10 ml or one to two teaspoonful per day.
  • Children aged 4-10 years: 2.5-5 ml or half to one teaspoonful per day.
  • Children from one month to 4 years of age: 0.25 ml/kg body weight per day.
• Concentrated Oral Solution (7.5 mg/ml) dose:
  • Adults and children over 10 years of age: 0.67-1.33 ml per day.
  • Children aged 4-10 years: 0.33-0.67 ml per day.

*Please adhere to the recommendations of a healthcare professional while consuming the medication.

Interactions

Concurrent usage of diuretics or adreno-corticosteroids may elevate the risk of electrolyte imbalance if consumed excessively. Simultaneous administration of antibiotics might diminish the laxative efficacy of Sopilax.

Contraindications

Sopilax is contraindicated in cases of ileus or intestinal obstruction, severe painful and/or feverish acute abdominal conditions (e.g., appendicitis) potentially accompanied by nausea and vomiting, acute inflammatory bowel diseases, severe dehydration, and known hypersensitivity to Sodium Picosulfate or any other component of the product.

Side Effects

Possible side effects may include hypersensitivity reactions, dizziness, syncope, vasovagal response, gastrointestinal disturbances, diarrhea, abdominal pain, abdominal cramps, nausea, and vomiting.

Pregnancy & Lactation

There are no reported adverse effects on pregnancy or the fetus attributed to Sopilax usage. However, its administration during the first trimester should be avoided. Clinical evidence indicates minimal excretion of the active moiety of sodium Picosulfate and its glucuronides in the milk of healthy lactating females.

Precautions & Warnings

Prolonged and excessive consumption of Sopilax may lead to fluid and electrolyte imbalance, as well as hypokalemia. Caution is advised for individuals with alcoholism, pregnant or breastfeeding women, children, and high-risk groups such as patients with liver disease or epilepsy.

Overdose Effects

Chronic overdose of laxatives may result in chronic diarrhea, abdominal pain, hypokalemia, secondary hyperaldosteronism, renal calculi, renal tubular damage, metabolic alkalosis, and muscle weakness.

Therapeutic Class

Sopilax belongs to the category of stimulant laxatives.

Storage Conditions

Store below 30°C, away from light and moisture, and out of reach of children.

Chemical Structure

• Molecular Formula: C18H15NNa2O9S2
• Chemical Structure: Sodium Picosulfate’s chemical structure.

Common Questions about Sopilax 10 mg Tablet

• What is Sopilax 10 mg Tablet?
  • Sopilax 10 mg Tablet falls under the class of laxatives.
• What are the uses of Sopilax 10 mg Tablet?
  • Sopilax 10 mg Tablet is employed for the treatment of constipation.
• How long does it take for Sopilax 10 mg Tablet to exhibit improvement in my condition?
  • Sopilax 10 mg Tablet should be consumed until an improvement in health conditions is observed.
• At what frequency should Sopilax 10 mg Tablet be taken?
  • Sopilax 10 mg Tablet should be consumed as per the doctor’s prescription.
• Should Sopilax 10 mg Tablet be taken on an empty stomach, before meals, or after meals?
  • Sopilax 10 mg Tablet is ideally taken at bedtime, requiring 6-8 hours to manifest its effects.
• What are the instructions regarding the storage and disposal of Sopilax 10 mg Tablet?
  • Sopilax 10 mg Tablet should be stored in a cool, dry place in its original packaging, ensuring it remains inaccessible to children and pets.
• Is Sopilax 10 mg Tablet safe for pregnant women?
  • Sopilax 10 mg Tablet is not recommended for pregnant women unless deemed necessary. Consultation with a healthcare provider is advised.
• Is Sopilax 10 mg Tablet safe for breastfeeding women?
  • Breastfeeding women are advised against consuming Sopilax 10 mg Tablet unless deemed necessary. Consultation with a healthcare provider is recommended.
• Is Sopilax 10 mg Tablet habit-forming?
  • No cases of addiction have been reported thus far.
• What should I do if I miss a dose of Sopilax 10 mg Tablet?
  • Take Sopilax 10 mg Tablet as soon as you remember. However, if it’s nearing the time for the next dose, adhere to your regular schedule and avoid doubling the dose.

Quick Tips

• Alongside Sopilax 10 mg Tablet, maintaining a fiber-rich diet comprising whole grain bread and cereals, bran, fruits, and green leafy vegetables is essential for sustaining healthy bowel function.
• Limit the usage of Sopilax 10 mg Tablet to one week unless otherwise prescribed by a healthcare professional, as prolonged consumption may result in dependency on its laxative effects.
• Consume Sopilax 10 mg Tablet at least 2 hours apart from other medications to prevent potential interference with their absorption.
• Preferably take Sopilax 10 mg Tablet at bedtime, allowing 6 to 8 hours for its effects to take place.