Rynex 0.05% Nasal Drops

Indications

Rynex is effective for alleviating nasal congestion linked to various conditions, including acute and chronic rhinitis, the common cold, sinusitis, upper respiratory allergies, epistaxis, and hay fever. It also serves as a nasal decongestant in cases of otitis media.

Pharmacology

Oxymetazoline Hydrochloride, an imidazoline derivative and sympathomimetic amine, acts as a direct agonist at α-adrenoceptors while showing no activity on β-adrenoceptors. When applied topically to the nasal mucosa, it induces rapid and prolonged vasoconstriction of arterioles, which decreases blood flow and reduces swelling in the mucosa. This mechanism enhances airway potency and facilitates better drainage of the nasal sinuses.

Dosage

Oxymetazoline Nasal Spray:

• Adults and Children (6 years and older): 2-3 sprays in each nostril twice daily for 3-5 days.
• Elderly: No dosage adjustment is necessary.
• Children under 6 years: Not recommended.

Oxymetazoline Nasal Drops:

• Adults & Children (6 years and older): 2-3 drops of 0.05% solution in each nostril twice daily.
• Children (2-5 years): 2-3 drops of 0.025% solution in each nostril twice daily.

Consult a healthcare professional before use.

Administration

How to Use the Nasal Spray:

1. Shake the bottle gently and remove the dust cover.
2. Hold the spray with your fingers on either side of the nozzle and your thumb underneath. Press down until a fine mist appears. If it’s your first use or it hasn’t been used in a week, prime the spray by pressing several times until it releases a mist.
3. Gently blow your nose to clear nostrils.
4. Close one nostril and insert the applicator into the open nostril. Tilt your head slightly forward and keep the spray upright. Inhale through your nose while firmly pressing the applicator to release a spray.
5. Exhale through your mouth.
6. Repeat for the other nostril as needed.

Cleaning: Clean the nasal spray weekly by following these steps:

1. Remove the dust cover.
2. Detach the nasal applicator.
3. Wash both components in warm water.
4. Shake off excess water and let them air dry away from heat.
5. Reattach the applicator and replace the dust cover.

Consult a healthcare professional before use.

Interaction

Rynex should not be administered to individuals taking MAO inhibitors or within 14 days of stopping such treatment.

Contraindications

Avoid use in patients with cardiovascular conditions, hyperthyroidism, prostatic enlargement, angle-closure glaucoma, or hypersensitivity to any ingredients.

Side Effects

Common side effects may include local irritation and dryness in the mouth and throat. Temporary sensations of burning, stinging, sneezing, or increased nasal discharge can occur.

Pregnancy & Lactation

The safety of Oxymetazoline Hydrochloride Nasal Spray during pregnancy and breastfeeding has not been confirmed, but it is generally not considered hazardous.

Precautions & Warnings

Avoid contact with the eyes. Do not use the spray for more than seven consecutive days without medical guidance. Prolonged use may lead to rebound nasal congestion.

Overdose Effects

An overdose may result in local irritation and rebound congestion. Treatment should be symptomatic.

Therapeutic Class

Nasal Anti-histamines, Decongestants, and Other Nasal Preparations.

Storage Conditions

Store below 30°C in a dry place, away from light. Do not refrigerate or freeze. Keep out of reach of children.