Remus 30gm

Indications

Remus ointment effectively treats moderate to severe atopic dermatitis, providing relief for patients who cannot use conventional therapies due to potential risks or lack of responsiveness. It’s also beneficial for various skin conditions like psoriasis, vitiligo, and allergic contact dermatitis.

Pharmacology

Containing tacrolimus, an immunomodulator, Remus ointment inhibits T-lymphocyte activation, reducing inflammation in affected areas. Its mechanism involves binding to intracellular proteins, ultimately suppressing the inflammatory cascade.

Dosage & Administration

For adults, apply a thin layer of Tacrolimus ointment twice daily on affected areas, continuing treatment for one week post-symptom clearance. Pediatric dosages vary based on age. Elderly patients (>65 years) can use Tacrolimus ointment with no distinct adverse events.

Interaction

Although formal interaction studies haven’t been conducted, caution is advised when administering Tacrolimus ointment alongside CYP3A4 inhibitors. Examples include erythromycin and ketoconazole.

Contraindications

Tacrolimus ointment is contraindicated in patients with hypersensitivity to Tacrolimus or its components.

Side Effects

Rare side effects include skin burning, pruritus, and flu-like symptoms, with minimal systemic effects observed.

Pregnancy & Lactation

Pregnancy Category C. While systemic absorption is minimal, caution is recommended during breastfeeding due to potential adverse effects on infants.

Precautions & Warnings

Exercise caution in patients predisposed to skin infections. Safety in patients with generalized erythroderma hasn’t been established.

Overdose Effects

Not for oral use. Accidental ingestion may lead to adverse systemic effects; seek medical advice if ingestion occurs.

Therapeutic Class

Immunomodulators

Storage Conditions

Store below 30°C, away from light, and out of children’s reach.