Indications
REMMO MUPS tablets are prescribed for Gastro-esophageal Reflux Disease (GERD), reducing the risk of NSAID associated gastric ulcers, H. pylori eradication (Triple therapy), and managing Zollinger-Ellison syndrome and idiopathic hypersecretion.
Composition
- Esomeprazole MUPS 20 Tablet: Contains 20 mg Esomeprazole (as Esomeprazole Magnesium Trihydrate USP).
- Esomeprazole MUPS 40 Tablet: Contains 40 mg Esomeprazole (as Esomeprazole Magnesium Trihydrate USP).
Description
MUPS stands for Multiple-Unit Pellet System, a technology that enhances drug absorption and reduces gastric residence time. It ensures uniform drug release, rapid dissolution, and minimized dose dumping.
Pharmacology
Esomeprazole inhibits gastric acid production by blocking the proton pump in gastric parietal cells, useful in treating gastric and duodenal ulcers.
Dosage
Varies by condition, typically administered once or twice daily depending on therapeutic needs and patient age.
Administration
REMMO MUPS tablets should be swallowed whole with liquid; they should not be chewed or crushed.
Interaction
REMMO may interact with drugs metabolized by CYP2C19 and CYP3A4 enzymes, affecting their plasma levels.
Contraindications
Avoid REMMO in patients with known hypersensitivity to Esomeprazole or its components.
Side Effects
Common side effects include headache, diarrhea, and nausea, similar in short and long-term treatments.
Pregnancy & Lactation
Use caution during pregnancy and breastfeeding due to potential risks.
Precautions & Warnings
Monitor use in patients with severe liver or renal impairment. Long-term use may slightly increase fracture risk in certain patients.
Storage Conditions
Store below 25ºC in a cool, dry place away from light, and keep out of children’s reach.
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