Reducid

Indications

Reducid is primarily prescribed for the treatment of:

• Gastric ulcers
• Duodenal ulcers
• Anastomotic ulcers
• Acute stress ulcers
• Reflux esophagitis
• Zollinger-Ellison syndrome

It is also effective for managing both acute gastritis and chronic gastritis during acute exacerbations.
Always follow the advice of a registered healthcare professional before taking any medication.

Pharmacology

Reducid contains Famotidine, a potent H2-receptor antagonist that works by blocking the action of histamine on the H2 receptors in the stomach’s parietal cells. This action effectively reduces gastric acid secretion, including basal, overnight, and pentagastrin-stimulated acid production. The binding of Famotidine to the H2 receptor is slowly reversible, ensuring long-lasting effects.

Dosage & Administration

Tablet:

• For Gastric Ulcers, Duodenal Ulcers, Anastomotic Ulcers, Upper Gastrointestinal Hemorrhage, Reflux Esophagitis, and Zollinger-Ellison Syndrome:
  • Adults: 20 mg twice daily (morning and evening) or 40 mg once daily before bedtime.
• For Acute and Chronic Gastritis Exacerbation:
  • Adults: 20 mg twice daily or 40 mg once daily before bedtime, with dose adjustments based on age and severity of symptoms. Most patients experience ulcer healing within 4-8 weeks.
  • For maintenance therapy: 20 mg once daily, or as prescribed by a healthcare provider.

Powder for Suspension:

• For Gastroesophageal Reflux Disease (GERD):
  • Infants (<1 year): 0.5 mg/kg/dose once daily for up to 8 weeks.
  • 3 to 11 months: 0.5 mg/kg/dose twice daily for up to 8 weeks.
  • 1 to 2 months: 0.5 mg/kg/dose once daily for up to 8 weeks.
  • Neonates: 0.5 mg/kg/dose, max once daily for up to 8 weeks.
• For Children (1-16 years):
  • GERD: 1 mg/kg/day, divided into two doses, up to 40 mg twice daily.
  • Duodenal Ulcer: 0.5 mg/kg/day at bedtime or divided into two doses, up to 40 mg/day.
  • Peptic Ulcer: 0.5 mg/kg/day at bedtime or divided into two doses, up to 40 mg/day.
  • Maintenance Therapy: 40 mg once daily at night.
  • Reflux Esophagitis: 2 mg/kg/day.
  • Zollinger-Ellison Syndrome: 40 mg three times daily.

Always use Reducid under the guidance of a qualified healthcare professional.

Drug Interactions

No significant drug interactions have been reported with Reducid. It does not interact with the cytochrome P450 enzyme system, minimizing the risk of interference with other medications.

Contraindications

Reducid should not be used if there is a known hypersensitivity to any of its ingredients.

Side Effects

While rare, some possible side effects of Reducid include:

• Skin rashes
• Constipation or diarrhea
• Dry mouth
• Nausea and vomiting
• Tachycardia
• Elevated blood pressure
• Headaches
• Drowsiness or insomnia

Pregnancy & Lactation

Reducid is categorized as Pregnancy Category B, meaning there are no adequate studies on pregnant women. It should be used during pregnancy only if absolutely necessary. Caution is advised when administering this drug to breastfeeding women.

Precautions & Warnings

• The drug should be used at the lowest effective dose, especially in elderly patients or those with renal failure or liver disorders.
• Always consult with a healthcare provider before starting treatment to ensure the right dosage and course of therapy.

Storage Conditions

• Store Reducid at temperatures below 30°C, away from direct light and moisture.
• Keep out of reach of children.