Name: Phylopen PFS
Brand: Square Pharmaceuticals PLC
SKU: 18721
Price: 80.00 BDT
Availability: InStock

Phylopen PFS

80.00৳ Pcs

Phylopen, produced by Square Pharmaceuticals PLC, is an antibiotic designed
Indicated for Gram-positive bacterial infections, including those caused by penicillinase-producing staphylococci
Effective in treating various infections such as skin and soft tissue infections, respiratory tract infections, osteomyelitis, and urinary tract infections
Administered orally or parenterally, with dosages adjusted based on age and severity of infection
Caution advised for patients with hepatic dysfunction or renal impairment
Available in both oral and parenteral forms for convenient administration
Contraindicated in patients allergic to penicillin

Brand

Square Pharmaceuticals PLC

Generics

Flucloxacillin Sodium

Type

Suspension

Size

100 ML

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Indications

Phylopen treats infections caused by Gram-positive organisms, including those produced by penicillinase-producing staphylococci. Indicated for various conditions such as skin and soft tissue infections, respiratory tract infections, osteomyelitis, enteritis, endocarditis, urinary tract infection, meningitis, septicaemia caused by Phylopen-sensitive organisms, and as prophylaxis during major surgical procedures.

Pharmacology

Flucloxacillin, an isoxazolyl penicillin, inhibits bacterial cell wall formation, particularly against penicillinase-producing staphylococci. Acts as a bactericidal antibiotic by interfering with peptidoglycan synthesis, leading to bacterial cell wall weakening and rupture.

Dosage

Oral administration: Adults typically take 250 mg four times daily, with dosages doubled in severe infections. Children’s doses vary by age. Parenteral administration: Intramuscular or intravenous injections are administered four times daily, with doses adjusted based on severity.

Administration

Oral doses should be taken an hour before meals, as advised by a healthcare professional.

Interaction

Concurrent use may increase Phylopen levels in the blood for extended periods.

Contraindications

Contraindicated in patients with penicillin hypersensitivity.

Side Effects

Common side effects include gastrointestinal disturbances, rashes, urticaria, purpura, fever, and interstitial nephritis.

Pregnancy & Lactation

Classified as US FDA Pregnancy Category B; caution advised during pregnancy and lactation due to excretion in human milk.

Precautions & Warnings

Caution in patients with hepatic dysfunction or allergic diathesis.

Use in Special Populations

Adjustments needed in severe renal failure (creatinine clearance <10 ml/min).

Therapeutic Class

Penicillinase-resistant penicillins.

Reconstitution

For other routes, such as intraarticular or intrapleural, specific doses are dissolved as necessary.

Storage Conditions

Store in a dry, cool place, away from light and heat, and keep out of reach of children.