Pearl-B 2500

Indications:

Pearl-B is used to treat:

• Hair loss and thinning hair
• Weak, brittle, or splitting nails
• Eczema and dermatitis

Note: Always follow your healthcare provider’s advice when using Pearl-B.

Composition:

Each tablet contains Biotin, an essential vitamin (Vitamin H) that plays a critical role in numerous bodily functions such as fatty acid synthesis, amino acid metabolism, and gluconeogenesis.

Pharmacology:

Biotin is vital for various physiological processes, including the metabolism of fats, proteins, and carbohydrates. It acts as a cofactor in enzymatic processes that are crucial for healthy skin, hair, and nails. Biotin is involved in the carboxylation of pyruvate and acetyl-CoA, key reactions for energy production.

Biotin plays a major role in epidermal cell growth and differentiation, making it essential for the renewal and formation of skin, hair, and nails. Its deficiency may lead to symptoms like hair loss, dermatitis, and other skin issues. Biotin is widely prescribed to address hair loss, making it a popular nutritional supplement.

Dosage & Administration:

Biotin dosage varies by condition and age group:

• Adults: Typically 1-3 tablets per day, or as directed by a healthcare provider.
• Children (1 week – 2 years): For biotin deficiency-related conditions such as seizures and developmental delay, the recommended dose is 5-10 tablets per day, crushed and mixed with water or juice, or as prescribed by a physician.

Recommended Dietary Allowance (RDA):

• Infants:
  0-6 months: 5 mcg/day
  7-12 months: 6 mcg/day
• Children:
  1-3 years: 8 mcg/day
  4-8 years: 12 mcg/day
  9-13 years: 20 mcg/day
  14-18 years: 25 mcg/day
• Adults:
  ≥19 years: 30 mcg/day
  Pregnancy: 30 mcg/day
  Lactation: 35 mcg/day

Note: Always consult your healthcare provider before use.

Interaction:

• Anticonvulsant drugs may lower the plasma levels of Pearl-B.
• Antibiotic use can reduce the contribution of biotin from the body’s microbiota.
• Raw egg whites may interfere with the absorption of biotin in the body.

Contraindications:

Pearl-B should not be used by individuals with a known hypersensitivity to any of its ingredients.

Side Effects:

Pearl-B is generally well-tolerated when taken as recommended. No toxicity has been reported even with high doses (up to 200 mg orally or 20 mg intravenously per day).

Pregnancy & Lactation:

Clinical data regarding the safety of Pearl-B during pregnancy and lactation is insufficient. Consult your healthcare provider before use in these conditions.

Therapeutic Class:

Herbal and Nutraceuticals

Storage Conditions:

• Store in a cool, dry place, away from light and moisture.
• Keep out of reach of children.