Neosten VT

Indications

Neosten VT rectal preparation is designed for the relief of vaginal itching, burning, and discharge linked to recurrent vaginal yeast infections (Vaginal Candidiasis). It is also effective for treating vaginitis caused by Candida species and mycotic infections complicated by other microorganisms sensitive to this treatment.

Pharmacology

Clotrimazole, the active ingredient in Neosten VT, is a broad-spectrum antifungal medication used to treat various dermal infections. It targets pathogenic dermatophytes, yeasts, molds, and certain bacteria, including Staphylococci and Trichomonas. Clotrimazole works by disrupting the cell wall permeability of fungi, inhibiting ergosterol synthesis at lower concentrations, and causing additional membrane damage at higher doses.

Dosage

For Clotrimazole 100 mg & 200 mg Vaginal Preparation:

• Initial Infections: Typically, a 3-day course is sufficient for Candida vaginitis. Insert one Clotrimazole 200 mg vaginal preparation deeply into the vagina for three consecutive nights. The best method is to lie on your back with knees slightly bent.
• Recurrent Infections: A 6-day treatment is generally recommended. For six consecutive nights, insert one Clotrimazole 100 mg vaginal preparation deeply into the vagina. For severe cases, use two Clotrimazole 100 mg tablets (one in the morning and one in the evening) or one Clotrimazole 200 mg tablet daily for 6-12 days. Ensure treatment is completed before menstruation begins, and consider treating your partner with Clotrimazole cream to prevent re-infection.

For Clotrimazole 500 mg Vaginal Preparation:

• Single Dose Treatment: Insert one 500 mg vaginal tablet deeply into the vagina as a single dose. This is most effective when lying on your back with knees slightly bent. To prevent re-infection, treat your partner simultaneously with Clotrimazole cream.

Clotrimazole vaginal preparations are colorless and will not stain underwear.

Administration

1. Pull out the applicator plunger until it stops.
2. Place a vaginal tablet into the applicator.
3. Insert the applicator deeply into the vagina (best performed while lying on your back).
4. Push the plunger fully to release the tablet into the vagina. Remove the applicator.
5. After use, remove the plunger from the applicator, wash it with warm soapy water, rinse, and dry thoroughly.

Note: Pregnant women should follow their physician’s guidance when using this medication.

Interactions

There is no available information regarding drug interactions.

Contraindications

Neosten VT is contraindicated for individuals with known hypersensitivity to any of its components.

Side Effects

Due to minimal absorption through the vaginal mucosa, systemic effects are unlikely. Local tolerance is generally good, though occasional irritation or a burning sensation may occur. These symptoms are usually not severe.

Pregnancy & Lactation

Clotrimazole should be used during pregnancy only if deemed necessary by a physician. It is poorly absorbed systemically after vaginal or skin application. No adverse effects have been observed in women during the second or third trimesters. The presence of Clotrimazole in breast milk is unknown. Use Clotrimazole suppositories during pregnancy only under medical supervision.

Therapeutic Class

Topical Antifungal Preparations for Vaginal and Vulval Conditions

Storage Conditions

Store below 25°C, away from light and moisture. Keep out of reach of children.