Neocilor

Indications

Neocilor is prescribed for alleviating symptoms related to seasonal and perennial allergic rhinitis, including sneezing, nasal discharge, itching, nasal congestion, ocular itching, tearing, redness, palate itching, and coughing. Additionally, it provides relief for symptoms associated with chronic idiopathic urticaria, effectively reducing itching and the size and quantity of hives.

Consult your registered healthcare provider before using this medication.

Pharmacology

Desloratadine, the primary active metabolite of Loratadine, is a non-sedating, long-acting tricyclic histamine antagonist that selectively targets H1-receptors. It also prevents histamine release from human mast cells, contributing to its efficacy in managing allergic symptoms.

Dosage & Administration

Pediatric Drops:

• Children aged 6-11 months: 2 ml once daily.
• Children aged 1-2 years: 2.5 ml once daily.

Syrup:

• Children aged 6-11 months: 2 ml once daily.
• Children aged 1-5 years: 2.5 ml once daily.
• Children aged 6-11 years: 5 ml once daily.
• Adults and children over 12 years: 10 ml once daily.

Tablets:

• Adults and children aged 12 years and older: 1 tablet daily.

Consult your registered healthcare provider before using this medication.

Interactions

No significant drug interactions have been observed.

Contraindications

Desloratadine is contraindicated in individuals with hypersensitivity to this medication, its components, or Loratadine.

Side Effects

Less frequent side effects may include headaches, nausea, fatigue, dizziness, pharyngitis, dyspepsia, and myalgia.

Pregnancy & Lactation

Pregnancy Category C. The safety of Desloratadine during pregnancy has not been established. It should only be used during pregnancy when absolutely necessary. Desloratadine is excreted in breast milk, so a decision should be made to either discontinue nursing or the medication, considering the importance of the drug to the mother.

Precautions & Warnings

For adult patients with liver or renal impairment, it is advised to start with one 5 mg tablet every other day, based on pharmacokinetic data. Special consideration should be given to patients with a medical or family history of seizures.

Use in Special Populations

Desloratadine is recommended for use in children and adolescents.

Overdose Effects

No significant adverse effects have been reported in cases of overdose.

Therapeutic Class

Non-sedating antihistamines.

Storage Conditions

Store in a cool, dry place, away from light. Maintain a temperature below 30°C. Keep all medications out of children’s reach.