Nazolin 0.05%

Indications

Nazolin is designed to relieve nasal congestion caused by various conditions such as acute or chronic rhinitis, common colds, sinusitis, upper respiratory allergies, epistaxis, and hay fever. It is also effective as a nasal decongestant for otitis media.

Pharmacology

Nazolin contains Oxymetazoline Hydrochloride, an imidazoline derivative and sympathomimetic amine. This compound acts directly on α-adrenoceptors and does not affect β-adrenoceptors. When applied topically to the nasal mucosa, Oxymetazoline Hydrochloride causes rapid and sustained vasoconstriction of the nasal arterioles. This reduces blood flow, minimizes mucosal swelling, and enhances nasal airway potency and sinus drainage.

Dosage

Oxymetazoline Nasal Spray:

• Adults and Children (6 years and older): 2-3 sprays per nostril twice daily for 3-5 days.
• Elderly: No dosage adjustment required.
• Children under 6 years: Not recommended.

Oxymetazoline Nasal Drops:

• Adults & Children (6 years and older): 2-3 drops of 0.05% solution per nostril twice daily.
• Children (2-5 years): 2-3 drops of 0.025% solution per nostril twice daily.

Always use as directed by a physician.

Administration

Using the Nasal Spray:

1. Shake the bottle gently and remove the dust cover.
2. Hold the bottle with your forefinger and middle finger on either side of the nozzle, and your thumb underneath. Press down until a fine mist appears. If using for the first time or after a break of a week or more, pump several times until a mist emerges.
3. Gently blow your nose to clear your nostrils.
4. Close one nostril and insert the applicator into the open nostril. Tilt your head forward slightly, keep the spray upright, and inhale through your nose as you press down firmly on the applicator to release a spray.
5. Exhale through your mouth.
6. Repeat in the other nostril if needed.

Cleaning the Nasal Spray:

1. Remove the dust cover.
2. Gently detach the nasal applicator.
3. Wash the applicator and dust cover in warm water.
4. Shake off excess water and let dry at room temperature. Avoid using additional heat.
5. Reattach the applicator and dust cover.

Always use as directed by a physician.

Interaction

Nazolin should not be used by patients currently taking MAO inhibitors or those who have taken them within the past 14 days.

Contraindications

Nazolin is contraindicated for individuals with cardiovascular disease, hyperthyroidism, prostatic enlargement, angle-closure glaucoma, or hypersensitivity to any of its components.

Side Effects

Possible side effects include local irritation, dryness of the mouth and throat, and temporary discomfort such as burning, stinging, sneezing, or increased nasal discharge.

Pregnancy & Lactation

The safety of Oxymetazoline Hydrochloride Nasal Spray during pregnancy and lactation has not been firmly established. However, it is not expected to pose a significant risk.

Precautions & Warnings

Avoid contact with eyes. Do not use the spray for more than seven days without medical advice. Overuse or prolonged use may lead to recurrence or worsening of nasal congestion.

Overdose Effects

Overdose may cause local irritation and rebound congestion. Symptomatic treatment is generally sufficient.

Therapeutic Class

Nasal Anti-histamine Preparations, Nasal Decongestants, & Other Nasal Preparations

Storage Conditions

Store below 30°C in a dry place, protected from light. Do not refrigerate or freeze. Keep out of reach of children.