Napa Extra

Indications

This medication is effective for alleviating:

• Headaches
• Migraines
• Toothaches
• Neuralgia
• Fever
• Menstrual pain
• Sore throat
• Back pain
• Reducing fever
• General aches and pains associated with colds and flu

Pharmacology

Our formula combines Paracetamol and Caffeine for enhanced relief. Paracetamol acts as an analgesic and antipyretic with mild anti-inflammatory effects. Caffeine, a xanthine derivative similar to theophylline, improves Paracetamol’s absorption and penetration across cell membranes. It also raises the pain threshold and increases pain tolerance. Additionally, Caffeine helps elevate brain vessel tone, offering extra relief for migraines and headaches.

Dosage & Administration

• Adults: Take 1-2 tablets every 4-6 hours as needed, with a maximum of 8 tablets per day.
• Children: Not recommended for those under 12 years of age. Always follow your healthcare provider’s advice when taking this medication.

Interactions

• Anticonvulsants (e.g., phenytoin, barbiturates, carbamazepine) may reduce serum levels.
• Prolonged use can enhance the anticoagulant effects of warfarin and other coumarins.
• Accelerated absorption occurs with metoclopramide and domperidone.
• Serum levels may increase with probenecid and chloramphenicol.
• Colestyramine may reduce absorption if taken within 1 hour.
• Combining with phenothiazine can cause severe hypothermia.

Contraindications

• Do not use if you have severe renal impairment or liver disease (e.g., Viral Hepatitis).
• Avoid if you are hypersensitive to Paracetamol or Caffeine.

Side Effects

While typically mild, possible side effects include:

• Hematological issues like thrombocytopenia and leukopenia
• Pancreatitis
• Skin rashes and other allergic reactions

Pregnancy & Lactation

Consult your doctor before using this medication during pregnancy. It is generally safe to use while breastfeeding.

Precautions & Warnings

Use with caution in individuals with liver or kidney conditions, or those taking other hepatotoxic drugs. Avoid prolonged use without medical consultation.

Overdose Effects

Ingesting too much Paracetamol may cause:

• Nausea, vomiting, and abdominal pain within the first 24 hours
• Liver damage visible 12 to 40 hours post-ingestion
• Possible glucose metabolism issues and metabolic acidosis

Therapeutic Class

Non-opioid analgesics

Storage Conditions

Store in a cool, dry place away from light and moisture. Keep out of reach of children.