Indications
Gynepro is recommended for:
- Treating vaginal trichomoniasis
- Managing vaginal leucorrhoeas
- Addressing mixed vaginal infections (fungal or bacterial).
Composition
Each vaginal suppository includes:
- Metronidazole BP 200 mg
- Neomycin Sulphate BP 35000 IU
- Polymyxin B Sulphate BP 35000 IU
- Nystatin BP 100000 IU.
Pharmacology
Metronidazole, a nitroimidazole, effectively targets anaerobic bacteria and protozoa. Nystatin acts as a polyene antibiotic with antifungal properties. Neomycin, an aminoglycoside, exhibits bactericidal activity against certain gram-positive and gram-negative organisms. Polymyxin is effective against gram-negative bacteria, including Pseudomonas aeruginosa.
Dosage & Administration
Administer one suppository intravaginally at bedtime for 12 days or as prescribed by a healthcare provider.
Contraindications
Avoid in patients hypersensitive to Metronidazole, Neomycin Sulphate, Polymyxin B Sulphate, or Nystatin.
Side Effects
Potential side effects include skin rash and urticaria, occurring rarely.
Pregnancy & Lactation
Use caution during pregnancy and lactation.
Precautions & Warnings
Use with caution in patients with renal impairment.
Therapeutic Class
Belongs to drugs used in vaginal and vulval conditions.
Storage Conditions
Store in a cool, dry place away from light and out of reach of children.
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