Germicord

Indications

Germicord is recommended for preventing omphalitis (infection of the umbilical cord) in newborns.

Pharmacology

Chlorhexidine, a broad-spectrum biocide, is effective against Gram-positive and Gram-negative bacteria as well as fungi. It exhibits both bacteriostatic and bactericidal properties, depending on concentration, and kills by disrupting cell membranes. In vitro studies show Chlorhexidine can eliminate nearly 100% of these bacteria within 30 seconds. Its ability to destroy a wide range of microbes minimizes the risk of opportunistic infections. Chlorhexidine binds strongly to the skin due to its cationic nature. Data on topical use in neonates is limited, and there is no information on its metabolism following topical application.

Dosage

Topical Solution:

• Immediately after cutting the cord, apply 7.1% Chlorhexidine Gluconate solution to the tip, stump, and base of the umbilical cord.

Topical Gel:

• Apply 3 grams of gel once daily for seven days, following local umbilical cord care guidelines.
• For infants born before 32 weeks gestation or weighing less than 1.5 kg at birth, apply a single 3-gram dose within 24 hours of birth.
• Clean the umbilical cord stump and surrounding skin with a dry cloth before applying the gel. Ensure the entire umbilical cord is covered from the cut surface to the base. Wash hands before and after use.
• Do not use Chlorhexidine Gluconate gel with other products or occlusive dressings to avoid increased absorption through the skin.

Administration

Chlorhexidine ব্যবহারের পূর্বে ও পরে হাত ভালো করে সাবান ও পানি দিয়ে ধুয়ে ফেলুন। Chlorhexidine এর ড্রপার বোতল চেপে সলিউশনটি নবজাতকের জন্মের পরপর কাটা নাড়ীর অগ্রভাগ, চারপাশ ও গোড়ায় এমনভাবে লাগান যেন সম্পূর্ণ নাড়ীটি ভালো ভাবে ভিজে যায়। Chlorhexidine লাগানোর পর নাড়ী কোন কিছু দিয়ে মুছবেন না। একবার Chlorhexidine লাগানোর পর নাড়ী শুষ্ক রাখুন ও নাড়ীতে অন্য কোন কিছুই লাগাবেন না। চোখে লাগাবেন না। চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন।

Pregnancy & Lactation

Not applicable for the intended patient population.

Precautions & Warnings

• For external use only.
• Do not inject or ingest.
• Avoid contact with eyes and ears; do not use over large areas of the body.
• In case of eye contact, rinse thoroughly with clean water.
• Discontinue use and seek immediate medical help if any signs of allergic reactions or skin irritation occur.
• Hypersensitivity and skin irritation, including generalized allergic reactions and anaphylactic shock, have been reported, although very rarely.

Therapeutic Class

Bleaching and Disinfectants

Storage Conditions

Store below 25°C, protected from light and moisture. Keep out of reach of children.