Gatiflox Eye Drops

100.00৳ Drop (5ml)

  • Gatiflox Eye Drops are indicated for the treatment of bacterial conjunctivitis caused by specific Gram-positive and Gram-negative bacteria.
  • Formulated with Gatifloxacin, an effective 8-methoxyfluoroquinolone antibiotic, it works by inhibiting crucial enzymes involved in bacterial DNA processes.
  • Recommended dosage varies based on the concentration and age, ensuring optimal treatment for affected individuals.
  • Safe storage and proper administration are essential for efficacy, with precautions advised for pregnant and nursing women.
Brand

Incepta Pharmaceuticals Ltd

Generics

Gatifloxacin

Type

Ophthalmic Solution

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Description

Indications

Gatiflox Eye Drops are specifically formulated for the treatment of bacterial conjunctivitis resulting from susceptible strains of the following microorganisms:

Aerobic Gram-Positive Bacteria:
  • Corynebacterium propinquum
  • Staphylococcus aureus
  • Staphylococcus epidermidis
  • Streptococcus mitis
  • Streptococcus pneumoniae
Aerobic Gram-Negative Bacteria:
  • Haemophilus influenzae

Pharmacology

Gatifloxacin is an 8-methoxyfluoroquinolone antibiotic intended for topical ophthalmic use. Its antibacterial efficacy is primarily due to the inhibition of DNA gyrase and topoisomerase IV—crucial enzymes involved in bacterial DNA replication, transcription, and repair. The unique C-8-methoxy structure enhances its activity and reduces the likelihood of developing resistant strains of Gram-positive bacteria compared to non-methoxy counterparts.

Dosage & Administration

Gatifloxacin 0.3%: For effective treatment of bacterial conjunctivitis, the following dosage is recommended:

  • Days 1 and 2: One drop every two hours in the affected eye(s) while awake, up to 8 times daily.
  • Days 3 through 7: One drop up to 4 times daily while awake.

Gatifloxacin 0.5%: For patients aged 1 year and older:

  • Day 1: One drop every two hours in the affected eye(s) while awake, up to 8 times.
  • Days 2 through 7: One drop two to four times daily in the affected eye(s) while awake.

Note: Always follow your healthcare provider’s instructions for use.

Interactions

Currently, there are no specific drug interaction studies available for Gatiflox eye drops.

Contraindications

Gatifloxacin eye drops should not be used in patients with a known hypersensitivity to Gatifloxacin, other quinolones, or any components of the formulation. It is also contraindicated for injection subconjunctivally or direct application into the anterior chamber of the eye.

Side Effects

Commonly reported side effects include conjunctival irritation and increased tearing.

Pregnancy & Lactation

Due to a lack of adequate and well-controlled studies in pregnant women, Gatifloxacin eye drops should only be used during pregnancy if the potential benefits outweigh the risks to the fetus. It is unknown whether Gatifloxacin is excreted in breast milk, so caution is advised when administered to nursing mothers.

Precautions & Warnings

Patients should refrain from wearing contact lenses if experiencing symptoms of bacterial conjunctivitis. Additionally, care should be taken to avoid contaminating the dropper tip with any surface, including the eye or fingers.

Overdose Effects

An overdose of Gatiflox eye drops is unlikely to pose a serious health threat.

Therapeutic Class

Ophthalmic Antibacterial Agents

Storage Conditions

Store in a cool, dry place away from light. Keep out of reach of children. Discard any unused product 4 weeks after opening.

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