Femzole 2.5
200.00৳ Strip
- Femzole is a nonsteroidal aromatase inhibitor indicated for the adjuvant treatment of hormone receptor-positive early breast cancer in postmenopausal women, as well as for hormone-dependent advanced breast cancer.
- It reduces estrogen biosynthesis, which is crucial for managing and treating hormone-sensitive cancers.
- Femzole is administered orally at 2.5 mg daily and is typically used for up to 5 years or until relapse.
- Common side effects include hot flashes, fatigue, and joint pain, while rare side effects may involve liver issues and nervous disorders.
- Store Femzole below 30°C, away from light and moisture, and keep out of reach of children.
Brand |
Beximco Pharmaceuticals Ltd |
---|---|
Generics |
Letrozole |
Type |
Tablet |
Indications:
Adjuvant treatment of hormone receptor-positive early breast cancer in postmenopausal women. Extended adjuvant therapy following 5 years of tamoxifen. First-line treatment for hormone-dependent advanced breast cancer. Management of advanced breast cancer in postmenopausal women previously treated with antiestrogens. Pre-operative therapy to enable breast-conserving surgery in localized hormone receptor-positive breast cancer.
Pharmacology:
Mechanism of Action: Nonsteroidal aromatase inhibitor reducing estrogen biosynthesis. Pharmacokinetics: Rapid absorption, peak levels in 1-2 hours, and a plasma half-life of about 2 days.
Dosage & Administration:
Oral: 2.5 mg once daily; continue for 5 years or until relapse. Hepatic/Renal Impairment: No dose adjustment needed; close supervision for severe impairment.
Interactions:
May interact with cimetidine and warfarin, but clinically significant reactions are rare.
Contraindications:
Hypersensitivity, pregnancy, lactation, pre-menopausal women, and severe hepatic dysfunction.
Side Effects:
Common: Hot flashes, hypercholesterolemia, fatigue, sweating, joint pain, skin rash, and gastrointestinal issues. Rare: Nervous disorders, eye disorders, and significant liver issues.
Pregnancy & Lactation:
Not recommended due to potential teratogenicity; unknown if excreted in milk.
Precautions & Warnings:
Caution in hepatic dysfunction; possible fatigue and dizziness.
Overdose Effects:
Supportive care; dialysis may be helpful.
Therapeutic Class:
Hormonal Chemotherapy
Storage Conditions:
Store below 30°C, away from light and moisture, and keep out of reach of children.
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