Dormitol 7.5

Indications

Dormitol is recommended for:

• Short-term treatment of insomnia.
• Sedation before surgical or diagnostic procedures.

Description

Dormitol is a rapid-onset sleep aid with short duration, also possessing anxiolytic, anticonvulsant, and muscle-relaxant properties.

Pharmacology

Benzodiazepines such as Dormitol enhance the activity of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in the central nervous system, resulting in sedation, muscle relaxation, and amnesia.

Dosage & Administration

Oral Dosage:

• Adults: 7.5-15 mg daily.
• Elderly or debilitated patients: 7.5 mg.
• Premedication: 15 mg, 30-60 minutes pre-procedure.

Intravenous Administration:

• Endoscopic or Cardiovascular Procedures: 2.5 mg in healthy adults (adjust for severe illness or elderly).
• Induction of Anesthesia: 10-15 mg.

Intramuscular Administration:

• Adult: 0.07-0.1 mg/kg.
• Children: 0.15-0.20 mg/kg.
• Elderly or debilitated patients: 0.025-0.05 mg/kg.

Rectal Administration (for children):

• Preoperative sedation: 0.35-0.45 mg/kg, 20-30 minutes pre-anesthesia.

Interactions

Dormitol may potentiate the central sedative effects of various medications, including neuroleptics, antidepressants, analgesics, and antiepileptic drugs.

Contraindications

Avoid Dormitol in patients with severe respiratory or hepatic insufficiency, myasthenia gravis, sleep apnea syndrome, or known hypersensitivity to benzodiazepines.

Side Effects

Common side effects include initial drowsiness, confusion, fatigue, headache, and muscle weakness. Respiratory depression, fluctuations in vital signs, and apnea may occur with parenteral administration.

Pregnancy & Lactation

Use Dormitol with caution during pregnancy and avoid breastfeeding while taking it due to potential transfer into breast milk.

Precautions & Warnings

Administer Dormitol IV slowly to minimize adverse reactions.

Overdose Effects

Extreme overdoses may lead to coma, cardiorespiratory depression, and apnea. Flumazenil can be used as an antidote.

Therapeutic Class

Dormitol belongs to the therapeutic class of benzodiazepine hypnotics and sedatives.

Storage Conditions

Store Dormitol in a cool, dry place, away from light and moisture. Keep out of reach of children.