Celofen

Indications

Celofen is used for managing pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, toothaches, trauma, and lumbago.
Always use as directed by a registered healthcare professional.

Pharmacology

Celofen contains Aceclofenac, a powerful non-steroidal anti-inflammatory drug (NSAID) that offers both anti-inflammatory and analgesic effects. By inhibiting the cyclooxygenase enzyme, Aceclofenac reduces the production of prostaglandins, which are responsible for inflammation and pain. When taken orally, Aceclofenac is quickly and fully absorbed without alteration in the body.

Dosage & Administration

• Extended-Release Tablet: For adults, the typical dosage is 200 mg of Aceclofenac once daily, or as prescribed by your physician.
• Film-Coated Tablet: The recommended dose for adults is 100 mg, taken twice daily.
  Please follow the guidance of a registered healthcare professional for the appropriate dosage.

Drug Interactions

While no major drug interactions have been reported, caution is advised when using Celofen with the following medications:

• Lithium and Digoxin: May increase the plasma levels of both lithium and digoxin.
• Diuretics: May affect the effectiveness of diuretics.
• Anticoagulants: Can enhance the effects of blood-thinning medications.
• Methotrexate: May elevate plasma concentrations of methotrexate.

Contraindications

Celofen should not be used by individuals who have a known allergy to Aceclofenac or in those who experience asthma attacks triggered by aspirin or other NSAIDs.

Side Effects

Common side effects include gastrointestinal disturbances, dizziness, and rash. Most side effects are mild, but consult your healthcare provider if you experience any unusual symptoms.

Pregnancy & Lactation

The use of Aceclofenac is not recommended during pregnancy or breastfeeding unless the potential benefit to the mother outweighs the potential risk to the fetus or child.

Precautions & Warnings

Use Celofen with caution in individuals with active or suspected peptic ulcers, gastrointestinal bleeding, severe liver conditions, or kidney or heart problems. It is also advised to use this medication carefully in patients with a history of dizziness or skin reactions like urticaria (hives).

Use in Special Populations

There is limited clinical data on the use of Celofen in children, and its use in this group is not recommended unless directed by a healthcare provider.

Therapeutic Class

Celofen belongs to the following therapeutic classes:

• Osteoarthritis treatment
• Rheumatoid Arthritis medication
• Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

Storage Conditions

Store Celofen in a dry place, away from direct light and heat. Keep it out of the reach of children to ensure safety.