Antiscar

Indications

This gel serves as an effective treatment for various types of scars, including:

• Hypertrophic and keloid scars
• Scars resulting from surgery
• Scars from amputation, burns, and trauma
• Scars caused by traumatic tendon contracture

Pharmacology

Extract of Allium cepa: Derived from onion membrane, this extract exhibits anti-inflammatory effects by inhibiting the secretion of inflammatory mediators and anti-allergic effects. It also inhibits the growth of fibroblasts, particularly keloidal fibroblasts, and possesses bactericidal properties, promoting primary wound healing while preventing excessive scar formation.

Heparin: When applied locally, heparin inhibits fibroblast proliferation and increases tissue hydration, reducing irritation and inflammation.

Allantoin: Known for stimulating cellular proliferation and supporting healthy cell development, allantoin facilitates scar treatment by promoting epithelialization and the formation of elastic tissue.

Clinical Studies

Studies evaluating the efficacy of Extract of Allium cepa, Heparin & Allantoin gel have shown significant reduction in scar width and height following treatment. Notably, a reduction of 31.5% in mean scar width and 47.8% reduction of mean scar height were observed in a study involving 1,268 patients.

Dosage & Administration

Apply the gel to the affected area 3-4 times daily, gently massaging it for better penetration. Continue massaging in a circular motion until the gel is completely absorbed. Treatment duration may vary depending on the size and severity of the scar.

Safety

The gel is well-tolerated and safe for use, even in children and infants, as demonstrated in numerous clinical studies.

Interaction

No known drug interactions have been reported.

Contraindications

Avoid use in patients with known hypersensitivity to any of the gel’s ingredients.

Side Effects

While generally well-tolerated, rare cases of local irritations such as slight redness and itching may occur. These side effects typically do not necessitate discontinuation of treatment.

Pregnancy & Lactation

Use caution during pregnancy and lactation, as there are limited studies conducted in these populations.

Precautions & Warnings

During treatment, avoid excessive cold, UV exposure, and vigorous massage on fresh scars. Additionally, refrain from contact with eyes, nose, mouth, or other mucous membranes.

Storage Conditions

Store in a cool, dry place below 25°C, away from direct sunlight and moisture. Keep out of reach of children.