Alice 12
200.00৳ Strip
- Alice tablet provides effective treatment for a range of parasitic infections, including strongyloidiasis, onchocerciasis, filariasis, scabies, and head lice.
- Its active ingredient, Ivermectin, targets parasites by binding to specific chloride ion channels, leading to their demise.
- Recommended dosages, tailored to body weight, ensure precise and effective treatment.
- While generally well-tolerated, rare side effects may include gastrointestinal discomfort and skin reactions.
- Consultation with healthcare professionals is advised for personalized treatment plans and monitoring.
Brand
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Square Pharmaceuticals PLC |
|---|---|
Generics
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Ivermectin |
Indications
Alice tablet serves as an effective remedy for various conditions, including:
- Strongyloidiasis
- Onchocerciasis
- Filariasis
- Scabies
- Head lice
Strongyloidiasis of the intestinal tract: Alice is specifically recommended for the treatment of intestinal strongyloidiasis caused by the nematode parasite Strongyloides stercoralis. Extensive clinical studies have demonstrated high cure rates ranging from 64% to 100% after a single dose of 200-mcg/kg of Alice.
Onchocerciasis: Alice is suitable for the treatment of onchocerciasis due to the nematode parasite Onchocerca volvulus. Clinical trials conducted in onchocerciasis-endemic regions have supported its efficacy, with a recommended dosage designed to address the condition effectively.
Pharmacology
Ivermectin, the active ingredient in Alice, exhibits selective binding to glutamate-gated chloride ion channels in invertebrate nerve and muscle cells. This mechanism leads to increased membrane permeability to chloride ions, resulting in hyperpolarization of nerve or muscle cells and eventual parasite death.
Dosage & Administration
For both treatment and prophylaxis, specific dosages of Ivermectin based on body weight are recommended. These guidelines ensure optimal effectiveness and safety in addressing conditions such as strongyloidiasis and onchocerciasis.
Interactions
Reports suggest rare instances of increased INR (International Normalized Ratio) when Alice is co-administered with warfarin.
Contraindications
Alice is contraindicated in patients with hypersensitivity to any of its components.
Side Effects
Various adverse reactions have been reported, albeit rarely, with the use of Alice. These include gastrointestinal discomfort, nervous system-related symptoms, and skin reactions. Monitoring and consultation with healthcare professionals are advised if such reactions occur.
Pregnancy & Lactation
Ivermectin’s safety during pregnancy is not established, and caution is advised. Nursing mothers should consult healthcare providers before using Ivermectin due to its excretion in human milk.
Precautions & Warnings
Patients treated with Alice for onchocerciasis may experience reactions, including the Mazzotti reaction. Professional guidance and monitoring during treatment are essential.
Use in Special Populations
While Alice’s safety and efficacy have been demonstrated, caution is advised in pediatric and geriatric populations due to limited clinical data.
Therapeutic Class
Alice belongs to the anthelmintic class, offering targeted relief for parasitic infections.
Storage Conditions
To maintain efficacy, it’s recommended to store Alice in a dry place below 30°C, away from light, and out of reach of children.
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